Found 12 matching trials
MEK Inhibitor PD-325901 To Treat Advanced Non-Small Cell Lung Cancer PHASE2 MEK is a critical member of the MAPK pathway involved in growth and surviva...
Show More Location
Pfizer Investigational Site
Learn More & Join Trial
MEK Inhibitor PD-0325901 Trial in Adolescents and Adults With NF1 PHASE2 This phase II open label study will evaluate adolescents (≥ 16 years of age...
Show More Location
Children's Hospital Los Angeles
Learn More & Join Trial
A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma PHASE1 The purpose of this study is to find out whether mirdametinib in combinatio...
Show More Location
Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities)
Learn More & Join Trial
SJ901: Evaluation of Mirdametinib in Children, Adolescents, and Young Adults With Low-Grade Glioma PHASE1 This is an open-label, multi-center, Phase 1/2 study of the brain-penetrant...
Show More Location
St. Jude Children's Research Hospital
Learn More & Join Trial
PALBOCICLIB + PD-0325901 for NSCLC & Solid Tumors PHASE1 This research study is evaluating the experimental drug palbociclib in comb...
Show More Location
Dana Farber Cancer Institute
Learn More & Join Trial
Clinical Trial Evaluating the Safety and Efficacy of Chemoimmunotherapy Plus Short Course of Mek Inhibitor in First Line of Treatment of Metastatic Non Squamous Non Small Cell Lung Adenocarcinoma With PDL1 < 50 %. PHASE1 Monocentric study composed by 2 steps :
1. First step is a phase I with th...
Show More Location
Centre Georges-François Leclerc
Learn More & Join Trial
A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations PHASE2 Recent studies have demonstrated that growth of vascular malformations can ...
Show More Location
Peter MacCallum Cancer Centre
Learn More & Join Trial
MEK and MET Inhibition in Colorectal Cancer PHASE1 This trial is designed to try two new cancer drugs together for the first t...
Show More Location
Oxford University Hospital NHS Trust
Learn More & Join Trial
Mirdametinib Monotherapy in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF). PHASE1 This is a Phase 1/2a, open-label, non-randomized, multi-dose study of mirda...
Show More Location
Johns Hopkins Hospital
Learn More & Join Trial
Testing the Effectiveness of the Anti-cancer Drug, Mirdametinib, in Treating Relapsed, Refractory Chronic Lymphocytic Leukemia PHASE2 This phase II trial tests the effect of mirdametinib in treating patients w...
Show More Location
City of Hope Comprehensive Cancer Center
Learn More & Join Trial