Found 23 matching trials
Observational Study of the Use of Pegloticase (KRYSTEXXA®) in Refractory Chronic Gout N/A The primary purpose of this study is to observe patients being treated with...
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Rheumatology Associates, PC
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A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout PHASE3 The primary objective of this trial is to evaluate the effect of pegloticas...
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University of Alabama at Birmingham
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Study to Assess Pegloticase (KRYSTEXXA®) in Patients on Hemodialysis PHASE1 This is a Phase 1 single dose study conducted to evaluate the PK and PD of ...
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Davita Clinical Research
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Study of KRYSTEXXA® (Pegloticase) Plus Methotrexate in Participants With Uncontrolled Gout PHASE4 The purpose of this study is to assess the potential for pegloticase with m...
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University of Alabama
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Pegylated Recombinant Mammalian Uricase (PEG-uricase) as Treatment for Refractory Gout PHASE2 The purpose of this study is to determine whether PEG-uricase (a chemically...
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Duke University Medical Center
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REduCing Immunogenicity to PegloticasE (RECIPE) Study PHASE2 Pegloticase treatment for chronic refractory gout is limited by immunogenic...
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University of Alabama at Birmingham
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Study of Pegloticase (KRYSTEXXA®) Plus Methotrexate in Patients With Uncontrolled Gout PHASE4 The overall objective of the study is to assess the efficacy, safety, toler...
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Orthopedic Physicians Alaska
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A Study of Persons With Gout Who Do Not Respond to or Are Allergic to Conventional Therapy PHASE2 This is a randomized, open-label, multicenter, parallel-groups study of mul...
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Spain Rehabilitation Center
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A Phase 4, Open-label Study of KRYSTEXXA® (Pegloticase) Co-administered With Methotrexate (MTX) in Patients With Uncontrolled Gout (FORWARD OL) PHASE4 This trial is to assess efficacy, safety, blood levels and bodily effects o...
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Orthopedic Physicians Alaska
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A Trial to Investigate the Non-inferiority of Pegloticase Administered Every 4 Weeks (Q4W) With MTX Compared With Every 2 Weeks (Q2W) With MTX in Participants With Uncontrolled Refractory Gout PHASE4 The study consists of 24-week double-blind trial to evaluate the non-inferi...
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The University of Alabama at Birmingham (UAB)
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