Found 13 matching trials
Patients Treated for SCID (1968-Present) N/A Individuals with a past diagnosis of severe combined immune deficiency (inc...
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University of Alabama at Birmingham
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EZN-2279 in Patients With ADA-SCID PHASE3 The purpose of this study is to evaluate the safety, efficacy, and pharmaco...
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Children's Hospital Los Angeles
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Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to Methotrexate PHASE4 This study is conducted to evaluate the short (12 Weeks) and long term (104...
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MND-ADA Transduction of CD34+ Cells From Children With ADA-SCID PHASE2 Severe combined immune deficiency (SCID) may result from inherited deficien...
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University of California, Los Angeles
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Registry Study of Revcovi Treatment in Patients With ADA-SCID N/A This registry study is being conducted in patients with adenosine deaminase...
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University of California Los Angeles
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UNDERSTANDING THE T-CELL AND B-CELL RECEPTOR REPERTOIRE IN CHILDREN AND YOUNG ADULTS WITH ANTI-DRUG ANTIBODIES AGAINST PEG ASPARAGINASE N/A The aim of this sub study is to identify biomarkers in children and young a...
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Multiple Locations
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Lentiviral (LV) Gene Therapy for Adenosine Deaminase (ADA) Deficiency PHASE1 This is a historically controlled, non-randomized Phase I/II clinical trial...
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Great Ormond Street Hospital for Children NHS Foundation Trust
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Natural History Study of SCID Disorders N/A This study is a prospective evaluation of children with Severe Combined Imm...
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Enrolling By Invitation
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University of Alabama at Birmingham
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Gene Transfer Therapy for Severe Combined Immunodeficieny Disease (SCID) Due to Adenosine Deaminase (ADA) Deficiency: A Natural History Study N/A This study will monitor the long-term effects of gene therapy in patients w...
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National Human Genome Research Institute (NHGRI)
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Autologous CD34+ Hematopoietic Stem Cells Transduced ex Vivo With Elongation Factor 1 Alpha Shortened (EFS) Lentiviral Vector Encoding for the Human ADA Gene PHASE1 The aim of this study is to assess the safety and efficacy of autologous tr...
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Mattel Children's Hospital, UCLA
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