Found 6 matching trials
A Phase I Study of PLX038 in Patients With Advanced Solid Tumors
PHASE1This is a Phase I, open-label, two-arm, dose escalation study of PLX038 int...
Location
University of Texas MD Anderson Cancer Center
PLX038 for Treatment of Metastatic Platinum-resistant Ovarian, Primary Peritoneal, and Fallopian Tube Cancer
PHASE2This phase II trial tests whether pegylated SN-38 conjugate PLX038 (PLX038)...
Status
Active Not Recruiting
PLX038 in Primary Central Nervous System Tumors Containing MYC or MYCN Amplifications
PHASE1Background:
About 90,000 new cases of brain and spinal cord tumors are dia...
Location
National Institutes of Health Clinical Center
A Study on Tuvusertib (Oral ATR Inhibitor) in Combination With PLX038 (Topo1 Inhibitor) in Patients With Advanced Solid Tumors
PHASE1Phase I with a dose finding cohort, followed by expansion cohorts in pre-sp...
A Study to Evaluate the Efficacy and Toxicities of PLX038, in Patients With Locally Advanced or Metastatic Triple-negative Breast Cancer
PHASE2Single arm phase II study for with primary objective to evaluate the effica...
PLX038 (PEGylated SN38) and Rucaparib in Solid Tumors and Small Cell Cancers
PHASE1Background:
Drugs known as poly-adenosine diphosphate ribose polymerase (P...
Location
National Institutes of Health Clinical Center