Found 16 matching trials
Characterization of the Inhibitory Effects of Fevipiprant (QAW039) on Activation of Eosinophils and ILC2 Cells by Prostaglandin D2 Metabolites
NAThe aim of this study is to draw blood from patients with well-defined atop...
Location
Fraunhofer ITEM im CRC
A Proof-of-mechanism Study of Multiple, Oral Doses of Fevipiprant (QAW039) in COPD Patients With Eosinophilia
PHASE2This was an exploratory, randomized, subject- and investigator-blind, place...
Location
Novartis Investigative Site
The Impact of Tredaptive on Flow-Mediated Dilation in Cardiac Patients
PHASE4Laropiprant (LRP; Merck \& Co., Inc, Whitehouse Station, NJ, USA) is a pote...
Location
Leviev Heart Center, Sheba Medical Center
Pathways of Eicosanoid Metabolism
EARLY_PHASE1Prostaglandins are important signaling compounds formed from arachidonic ac...
Status
Enrolling By Invitation
Location
Vanderbilt University
Effect of OC459 on the Response to Rhinovirus Challenge in Asthma
PHASE2The aim of this study is to assess the effectiveness of a CRTH2 receptor an...
Location
St Mary's Hospital
Safety and Efficacy of QAW039 in Sputum Eosinophilia and Persistent Asthma
PHASE2This study will assess the safety and efficacy of QAW039 when added to curr...
Location
Novartis Investigative Site
Efficacy and Safety of Lertal® as an add-on to Standard Therapy for Allergic Rhinoconjunctivitis in Pediatrics
NAThe purpose of this study is to evaluate the efficacy and safety of Lertal®...
Location
Fondazione IRCCS Policlinico San Matteo
Determination of Lipocalin Type-prostaglandin (L-PGDS) in Blood, Urine, Vaginal Samples and Endometrial Ablation by Enzyme-linked Immunosorbent Assay
N/AProstaglandin D2 (PGD2) has anti-inflammatory activity, particularly via Li...
Study of the Tolerability and Pharmacokinetic of ZL-2102 With an Investigation of Food Effect in Healthy Male Subjects
PHASE1The first-in-man study are designed as below to assess safety, tolerability...
Location
Linear Clinical Research Unit
Mechanistic Study of Anti-inflammatory Effects of Fevipiprant in Patients With Eosinophilic Asthma.
PHASE2This is an exploratory, randomized, subject- and investigator-blinded, plac...
Location
Multiple Locations