Found 6 matching trials
Effect of Food on PC14586 in Healthy Volunteers and the PK of PC14586 in Healthy Japanese Volunteers PHASE1 This is a 2-part Phase 1 cross-over study to assess the effects of food on ...
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Parexel Early Phase Clinical Unit - Los Angeles
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A Study to Investigate the Effects of Acid Reducing Agents on Pharmacokinetics of PC14586 in Healthy Participants PHASE1 This study will assess the effect of a Proton Pump Inhibitor (PPI) (rabepra...
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Parexel International
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The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) PHASE1 The Phase 2 monotherapy portion of this study is currently enrolling and wi...
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University of California Irvine Chao Family Comprehensive Cancer Center
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AME Study of [14C]-PC14586 in Healthy Male Participants PHASE1 This study will assess the PK and rates of elimination and mass balance of ...
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Labcorp Clinical Research Unit Inc.
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A Study to Investigate the Effects of Multiple Doses of Rezatapopt on the Pharmacokinetics of Metformin, Rosuvastatin, Repaglinide, and Midazolam in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation. PHASE1 This study aims to evaluate the effects of rezatapopt on the pharmacokineti...
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A Study to Investigate the Effects of Itraconazole on the Pharmacokinetics of PC14586 in Healthy Participants PHASE1 The purpose of this study is to assess the effect of PC14586 pharmacokineti...
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