A PARG Inhibitor DAT-2645 Monotherapy in Patients with Advanced/Metastatic Solid Tumors Harboring BRCA1/2 Loss of Function Alterations And/or Other Defects in the DDR Pathway
PHASE1
The primary objective of the study is to evaluate the safety, tolerability,...
A Study in Ovarian Cancer Patients Evaluating Rucaparib and Nivolumab as Maintenance Treatment Following Response to Front-Line Platinum-Based Chemotherapy
PHASE3
This is a Phase 3, randomized, multinational, double-blind, dual placebo-co...
Secondary Cytoreduction Followed by Chemotherapy Versus Chemotherapy Alone in Relapsed Ovarian Cancer After PARPi Maintenance Treatment: a Multicentre, Open-label, Randomised, Phase 3 Trial
NA
This study aims to carry out a multi-center, randomized controlled study on...
Status
Recruiting
Location
Women's Hospital, Zhejiang University School of Medicine
BMN 673 (Talazoparib), an Oral PARP Inhibitor, in People With Deleterious BRCA1/2 Mutation-Associated Ovarian Cancer Who Have Had Prior PARP Inhibitor Treatment
PHASE2
Background:
\- The new drug BMN 673 (talazoparib) has been shown to fight ...
Status
Terminated
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike