Found 19 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea PHASE1 This is a phase 1, randomized regimen optimization study of PfSPZ Vaccine i...
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Baney Clinical Research Center
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Trial to Evaluate L9LS in Healthy Adults PHASE1 Background:
Malaria is a parasitic disease carried by mosquitoes in tropic...
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National Institutes of Health Clinical Center
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Controlled Human Malarial Infection by Intravenous Injection of Plasmodium Falciparum Sporozoites in Non-Immune Adults PHASE1 The study is designed to establish the best dose to safely infect healthy i...
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Eberhard Karls University of Tübingen, Germany
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Safety and Protective Efficacy of Genetically Attenuated PfSPZ-GA1 Vaccine in Healthy Dutch Volunteers PHASE1 This is a first-in-human, randomized clinical trial of PfSPZ-GA1 Vaccine (g...
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Leiden University Medical Center, Albinusdreef 2
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Phase 1 Clinical Trial With Controlled Human Malaria Infection (CHMI) to Evaluate the Safety and Efficacy of the Plasmodium Falciparum Vaccine Candidate FMP012 Administered Intramuscularly With AS01B Adjuvant System in Healthy Malaria-Naïve Adults PHASE1 The proposed study is a Phase 1 study with controlled human malaria infecti...
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Clinical Trials Center, WRAIR
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Effect of Plasmodium Falciparum Exposure and Sickle Cell Trait on Infection Rates and Kinetics After IV Administration of PfSPZ Challenge PHASE1 The study is designed to establish infectivity of Plasmodium falciparum spo...
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Centre de Recherches Médicales de Lambaréné
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A Study to Assess the Safety and Effectiveness of Two Experimental Malaria Vaccines PHASE1 Malaria is a major public health problem. There were around 240 million cas...
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Centre for Clinical Vaccinology & Tropical Medicine (CCVTM)
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