Found 111 matching trials
SBRT Combined With Osimertinib Compared With Osimertinib for Stage IV NSCLC NA This is a Prospective, Multicenter, Randomized Controlled study to evaluate...
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Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, Hubei, P. R. China
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Osimertinib With or Without Bevacizumab for EGFR- Mutant Non-small Cell Lung Cancer With Leptomeningeal Metastasis PHASE2 Leptomeningeal metastasis (LM) is a devastating and terminal complication o...
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Multiple Locations
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Study of Osimertinib + SRS vs Osimertinib Alone for Brain Metastases in EGFR Positive Patients With NSCLC PHASE2 This open-label, multicenter, randomized phase II study will evaluate the u...
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Active Not Recruiting
Location
BC Cancer, Vancouver Centre
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Phase 1/2 Study of Silevertinib (BDTX-1535) in Patients With Glioblastoma or Non-Small Cell Lung Cancer With EGFR Mutations PHASE1 BDTX-1535-101 is an open-label, Phase 1 dose escalation and Phase 2 multipl...
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Active Not Recruiting
Location
University of Alabama
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Aumolertinib With Chemotherapy or Alone Compared With Osimertinib in Patients With Epidermal Growth Factor Receptor-Mutant Non-Small Cell Lung Cancer PHASE3 Aumolertinib is a third-generation epidermal growth factor receptor (EGFR) ...
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Highlands Oncology Group
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A Window of Opportunity Study for Investigating Drug Tolerant Persister (DTP) to Neoadjuvant Osimertinib in Resectable Non-small Cell Lung Cancer (NSCLC) Harbouring EGFR Mutations NA Osimertinib is a third-generation EGFR (Epidermal growth factor receptor) T...
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Yonsei University Health System, Severance Hospital
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Study to Assess the Efficacy and Safety of Adjuvant Osimertinib in NSCLC With Uncommon EGFRm PHASE2 This is an open-label, multi-centre, single-arm study assessing the efficac...
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Active Not Recruiting
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Study to Assess the Effect of AZD9291 on the Blood Levels of Simvastatin in Patients With EGFRm+ NSCLC PHASE1 This is a Phase I, open-label, 2-part study in patients with a confirmed di...
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A Study to Investigate Safety and Efficacy of Osimertinib and Amivantamab in Participants With Non-small Cell Lung Cancer With Common Epidermal Growth Factor Receptor Mutations PHASE2 This study will assess the safety and efficacy of Osimertinib with Amivanta...
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Active Not Recruiting
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Phase II Study of AZD9291 in Advanced Stage NSCLC With EGFR and T790M Mutations Detected in Plasma Ct-DNA PHASE2 Circulating tumor DNA (ctDNA) is a highly specific and effective biomarker ...
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Pamela Youde Nethersole Eastern Hospital
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