Found 26 matching trials
Monitoring Response to Orkambi in Cystic Fibrosis Lung Disease by Inhaled Xenon MRI
N/AThis is an observational study for children with Cystic Fibrosis (CF) who a...
Status
Active Not Recruiting
Location
Cincinnati Children's Hospital Medical Center
Real-life Follow-up of Cystic Fibrosis Patients Treated With Ivacaftor+Lumacaftor (Orkambi*)
N/AThe purpose of the study is to examine the real-life safety and effectivene...
Location
Adult CF center, Service de Pneumologie, Cochin Hospital
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation
PHASE2The purpose of this study is to evaluate the safety and efficacy of treatme...
Location
Multiple Locations
Effect of Lumacaftor-ivacaftor on Glucose Handling and Tolerance in Cystic Fibrosis Phe508del
NAThe purpose of this research study is to find out if the combined therapy l...
Location
Multiple Locations
Response to CFTR Modulators in CF Patients Under 18 Years
N/ACFTR modulators should improve the prognosis of Cystic Fibrosis. Identifyin...
Location
Sermet-Gaudelus Isabelle
Longitudinal Assessment of Exercise Capacity and Vascular Function in Patients With CF
N/AThis project is an attempt to understand how Orkambi treatment affects exer...
Location
Georgia Prevention Institute
ICM to Evaluate the Activation of p.Phe508del-CFTR by Lumacaftor in Combination With Ivacaftor
N/AThe academic investigator - initiated trial will evaluate in a postapproval...
Location
Justus-Liebig-University
Real Life Evaluation of the Multi-organ Effects of Lumacaftor/Ivacaftor on F508del Homozygous Cystic Fibrosis Patients.
N/ABackground: Lumacaftor/Ivacaftor (LUM-IVA), a CFTR corrector-potentiator co...
Location
Multiple Locations
Bioequivalence and Food Effect Bioavailability Study of Lumacaftor Film-Coated Tablets
PHASE1The objective of this study is to assess bioequivalence of lumacaftor from ...
Location
BioPharma Services Inc.
GLPG2737 on Top of Orkambi in Subjects With Cystic Fibrosis
PHASE2This is a Phase IIa, multi-center, randomized, double-blind, placebo-contro...