Found 14 matching trials
Effect of Food on the Pharmacokinetics of Decitabine/Tetrahydrouridine Combination Capsules in Healthy Adult Subjects
PHASE1This study is to investigate the effect of a high fat meal on the pharmacok...
Location
Worldwide Clinical Trial
Randomized, Single-dose, Crossover Study of 4 Decitabine and Tetrahydrouridine (EPI01) Formulations in Healthy Subjects
PHASE1To study the pharmacokinetic profiles of decitabine and tetrahydrouridine (...
Location
Worldwide Clinical Trial
Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy
PHASE1Background:
Most patients who have surgery for cancer that has metastasize...
Location
Multiple Locations
A Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS)
PHASE1The goal of this clinical trial is to learn about the safety and effectiven...
Location
Montefiore Einstein Medical Center
A Study of Nicotinamide With Oral Tetrahydrouridine and Decitabine to Treat High Risk Sickle Cell Disease
PHASE1A randomized control trial in 20 subjects with sickle cell disease comparin...
Location
University of Illinois at Chicago College of Medicine
Modulation of Stem Cell Differentiation in Individuals With High Risk Clonal Haematopoiesis
PHASE2Clonal hematopoiesis (CH) is characterized by the overproduction of blood c...
Location
Canberra Health Services
Rational EpigenetiC Immunotherapy for SEcond Line Therapy in Patients With NSCLC: PRECISE Trial
PHASE2The purpose of this study is to assess whether treatment with the study dru...
Location
Center for Cancer Research
p53/p16-Independent Epigenetic Therapy With Oral Decitabine/Tetrahydrouridine for Refractory/Relapsed Lymphoid Malignancies
EARLY_PHASE1The purpose of this study is to evaluate how well the study drug works and ...
Location
Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer Center
To Study the Oral Bioavailability of a New Combination Formation of Decitabine and Tetrahydrouridine in Healthy Males
PHASE1This is an open-label, randomized, single-dose per period, two-period, cros...
Location
Worldwide Clinical Trails Early Phase Services
Study of Decitabine and Tetrahydrouridine (THU) in Patients With Sickle Cell Disease
PHASE1The purposes of this study are to observe if oral tetrahydrouridine and dec...
Location
University of Illinois at Chicago