Found 23 matching trials
An Open-Label Study to Investigate the Pharmacokinetics of Omacetaxine Mepesuccinate
PHASE1The purpose of this study is to determine the pharmacokinetic and safety pr...
Location
Teva Investigational Site 38045
AML-02: Omacetaxine With Standard-of-Care Induction With Cytarabine & Idarubicin in Newly-Diagnosed AML Patients
PHASE1This is a dose escalation study to evaluate Omacetaxine when given in combi...
Location
University of Illinois at Chicago
Homoharringtonine With Oral Gleevec in Chronic, Accelerated and Blast Phase Chronic Myeloid Leukemia (CML)
PHASE2This will be an open label, multi-center study of up to 77 patients with CM...
Location
Univ. of Texas M.D. Anderson Cancer Center
Study of Azacitidine Combined With Homoharringtonie Based Regimens in AML
PHASE2Rencent years have witnessed great progress of the treatment of acute myelo...
Location
Department of Hematology, Zhongda Hospital, Medical School of Southeast University
A Clinical Trial of Omacetaxine, Azacitidine, and Growth-Colony Stimulating Factor (G-CSF) for Myelodysplastic Syndromes (MDS)
PHASE1The purpose of this study is to determine the safety and establish the maxi...
Location
University of Florida Health Shands Cancer Hospital
Omacetaxine and Venetoclax for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Harboring Mutant RUNX1
PHASE1This phase Ib/II trial best dose, possible benefits and/or side effects of ...
Location
M D Anderson Cancer Center
Omacetaxine and Low Dose Cytarabine in Older Patients With Acute Myelogenous Leukemia (AML) and High-Risk Myelodysplastic Syndrome (MDS)
PHASE2The goal of this clinical research study is to learn if omacetaxine given w...
Location
University of Texas MD Anderson Cancer Center
Omacetaxine for Consolidation and Maintenance
PHASE2The purpose of this pilot study is to assess the safety and tolerability of...
Location
Emory University Winship Cancer Institute
Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia
PHASE2RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cel...
Location
University of Texas - MD Anderson Cancer Center
Omacetaxine and Decitabine in Acute Myelogenous Leukemia (AML) and Myelodysplastic Syndrome (MDS)
PHASE1This clinical research study is made up of 2 phases. The goal of Phase 1 of...
Location
University of Texas MD Anderson Cancer Center