Found 20 matching trials
Efficacy and Safety of Obeticholic Acid in the Treatment of Primary Biliary Cholangitis
PHASE3Obecholic acid is a modified bile acid and Farnesoid X receptor (FXR) agoni...
Location
Beijing Friendship Hospital
Effect of Heavy Alcohol Consumption on Farnesoid X Receptor (FXR) Signaling
NAThe main purpose of this study is to see whether heavy drinking will interf...
Location
Indiana University
Phase 3 Study of Obeticholic Acid in Patients With Primary Biliary Cirrhosis
PHASE3The main objectives of the study were to assess the effects of Obeticholic ...
Location
UC Davis Medical Center
Study of OCA in Combination With BZF Evaluating Efficacy, Safety and Tolerability in Participants With PBC
PHASE2Study to determine the effect of the investigational drug bezafibrate (BZF)...
Location
University of Alabama at Birmingham
Obeticholic Acid in Pediatric Subjects With Biliary Atresia
PHASE2This is a Phase 2, multicenter, open-label, single dose and multi-dose, dos...
Location
Clinques University Saint-Luc
Study of INT-747 as Monotherapy in Participants With Primary Biliary Cirrhosis (PBC)
PHASE2The primary hypothesis was that obeticholic acid (OCA) will cause a reducti...
Phase 4 Study of Obeticholic Acid Evaluating Clinical Outcomes in Patients With Primary Biliary Cholangitis
PHASE4Primary Biliary Cholangitis (PBC) is a serious, life-threatening, bile acid...
Location
Mayo Clinic Arizona
Obeticholic Acid in Bile Acid Diarrhoea
PHASE2The investigators propose to develop studies of obeticholic acid (OCA) in p...
Location
Hammersmith Hospital, Imperial College Healthcare NHS Trust
Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjects
PHASE1In participants with inadequate response/intolerance to ursodeoxycholic aci...
Location
GSK Investigational Site
Combination Obeticholic Acid (OCA) and Statins for Monitoring of Lipids (CONTROL)
PHASE2This Phase 2, double-blind, randomized, placebo-controlled, multicenter stu...
Location
St. Joseph's Hospital and Medical Center