Found 54 matching trials
Variance of Oral Methadone Dosage: Description of Implicated Factors N/A The purpose of this study is to describe clinical, pharmacokinetic and gene...
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hospital Lariboisière-Fernand-WidalCity: PARIS
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MOR-1 Expression in Colorectal Cancer and Disease-free Survival Relationship. Five-year Follow-up. N/A Colorectal cancer (CRC) is a global burden and one of the most frequent typ...
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Hospital Universitario La Fe
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Positron Emission Tomography (PET) Trial to Evaluate Target Occupancy of CVL-354 at Kappa and Mu Opioid Receptors in Brain Following Oral Dosing PHASE1 The primary purpose of this study is to assess the target occupancy at kapp...
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New Haven, Connecticut
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Long-acting Buprenorphine vs. Naltrexone Opioid Treatments in CJS-involved Adults PHASE4 This study seeks to compare the effectiveness of two medications used to tr...
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Yale University School of Medicine
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Genetic Effects on Dopamine Response to an Opiate PHASE2 Background:
\- Small differences in genes may alter responses to drugs. On...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Personalized Post-Operative Pain Management PHASE4 The main questions this study aims to answer are:
Does perioperative PGx p...
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Active Not Recruiting
Location
The University of Tennessee Graduate School of Medicine
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Naltrexone for Individuals of East Asian Descent PHASE2 This study will elucidate the pharmacogenetic effects of the Asn40Asp SNP o...
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UCLA Addictions Laboratory
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Evaluation of the Efficacy and Safety of ADL5945 for the Treatment of Opioid-induced Constipation in Adults Taking Opioid Therapy for Chronic Noncancer Pain PHASE2 Morphine and related opioid analgesics are known to slow gastrointestinal (...
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Multiple Locations
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Genetic Determinants of Opioids Analgesia NA The response to opioids varies greatly among individuals. Some of these var...
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Hadassah Medical Organization
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Opioid Modulation and Neural Reward Activation in Healthy Adults PHASE1 This is a double blind study of the effects of opioid antagonism on the bra...
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University of Colorado Anschutz Medical Campus
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