🤖 GLOBAL HEALTH OPTIMIZATION AGENT v3.0

🔬 Current Disease Focus:

Task Progress: 0%

👥 Active Problem Solvers

🌍 Experts collaborating globally

⚡ Current Task Assignment

🧬 Genetic Analysis

🔄 Matching experts to specific tasks

📊 Resource Allocation by Research Phase:

📚 Data Analysis

🧪 Experimental Design

🔬 Clinical Trials

💊 Treatment Development

Trial Search

Current Search Criteria:

Intervention: Nucleoside Reverse Transcriptase Inhibitors

Found 0 matching trials

Efficacy and Safety of Switching From Retrovir to Tenofovir or Abacavir in HIV-infected Patients

PHASE4

To evaluate the efficacy and safety of switching from Retrovir to Tenofovir...

Status

Completed

Location

Aarhus University Hospital

Start Date

2008-06

Trial ID

NCT00647244

Treatments Being Tested

Tenofovir disoproxil fumarate Abacavir

Prevention of HIV1 Mother to Child Transmission Without Nucleoside Analogue Reverse Transcriptase Inhibitors in the Pre-partum Phase. ANRS 135 Primeva

PHASE2

In the pre-partum phase the use of antiretroviral therapy for the mother du...

Status

Completed

Location

Hopital Pitie salpetriere

Start Date

2007-03

Trial ID

NCT00424814

Treatments Being Tested

Kaletra (lopinavir/ritonavir)Kaletra (lopinavir/ritonavir) + Combivir (zidovudine/lamivudine)

MARCH Central Nervous System Substudy

N/A

This substudy is a prospective, observational, open-label, randomised study...

Status

Completed

Location

Fundación IDEAA

Start Date

2012-06

Trial ID

NCT01637233

Treatments Being Tested

Arm 1 TNucleotide Analogue Reverse Transcriptase Inhibitors and Boosted Protease Inhibitors Arm 2 Maraviroc and Protease Inhibitors Arm 3 Maraviroc and Nucleotide Analogue Reverse Transcriptase Inhibitors

A Study to Evaluate the Pharmacokinetic Profile (How the Body Absorbs, Distributes, Metabolizes and Eliminates a Drug) of TMC125 Plus Tenofovir/Emtricitabine Once Daily With or Without Darunavir/r Once Daily in Antiretroviral (ARV) Naive HIV-1 Patients (Patients Have Never Received ARV Treatment).

PHASE2

The purpose of this study is to determine the pharmacokinetic profile of TM...

Status

Completed

Location

Multiple Locations

Start Date

2008-01

Trial ID

NCT00534352

Treatments Being Tested

TMC125; darunavir; ritonavir

Treatment Success and Failure in HIV-Infected Subjects Receiving Indinavir in Combination With Nucleoside Analogs: A Rollover Study for ACTG 320

PHASE2

Group A: To compare the time to confirmed virologic failure (2 consecutive...

Status

Completed

Location

Univ of Alabama at Birmingham

Start Date

TBD

Trial ID

NCT00000885

Treatments Being Tested

Indinavir sulfate Abacavir sulfate Nelfinavir mesylate Efavirenz Levocarnitine Adefovir dipivoxil Lamivudine Stavudine Zidovudine Didanosine

Evaluate the Efficacy and Safety of Azvudine in Preventing SARS-Cov-2 Infection in Household Contacts of Covid-19

PHASE2

A Phase II/III Randomized, Double-Blind, Placebo-Controlled Trial to Evalua...

Status

Unknown

Location

University of Malaya Medical Centre

Start Date

2022-12-29

Trial ID

NCT05633433

Treatments Being Tested

Azvudine Placebo

A Combination Efficacy Study in Africa of Two DNA-MVA-Env Protein or DNA-Env Protein HIV-1 Vaccine Regimens With PrEP

PHASE2

This international, multi-centre, double-blind vaccine study is a three-arm...

Status

Completed

Location

MRC/UVRI and LSHTM Uganda Research Unit

Start Date

2020-12-15

Trial ID

NCT04066881

Treatments Being Tested

Vaccine Group A: DNA-HIV-PT123 and AIDSVAX® B/E (weeks 0,4,24,48)Vaccine Group B: DNA-HIV-PT123 and CN54gp140+MPLA-L (weeks 0,4), then MVA and CN54gp140+MPLA-L (weeks 24,48)Vaccine Group C: Saline placebo (weeks 0,4,24,48)Control PrEP:TDF/FTC once daily (weeks 0-26)Experimental PrEP:TAF/FTC once daily (weeks 0-26)

Impact of Antiretroviral Therapy on Metabolic, Skeletal, and Cardiovascular Parameters

N/A

The U.S. Department of Health and Human Services (HHS) guidelines recommend...

Status

Completed

Location

USC CRS

Start Date

2009-06

Trial ID

NCT00851799

Treatments Being Tested

Emtricitabine/tenofovir disoproxil fumarate Ritonavir Atazanavir Raltegravir Darunavir

Differences Between Women and Men Taking a Combination of Indinavir, Ritonavir, Enteric-Coated Didanosine, and Stavudine Who Previously Took Anti-HIV Drugs

PHASE3

The purpose of this study is to see how safe and effective it is to give mu...

Status

Unknown

Location

East Bay AIDS Ctr

Start Date

2000-08

Trial ID

NCT00006397

Treatments Being Tested

Indinavir sulfate Ritonavir Stavudine Didanosine

Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study

PHASE1

Recent studies have identified an association between Alzheimer's Disease (...

Status

Active Not Recruiting

Location

National University Hospital

Start Date

2025-06-30

Trial ID

NCT07210528

Treatments Being Tested

Emtricitabine (FTC)Descovy® (TAF/FTC)Placebo to Match Emtricitabine 200mg/Tenofovir Alafenamide 25 mg.Placebo Capsules to Match Emtricitabine Capsules, 200mg.

Previous Next