Found 229 matching trials
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) PHASE3 In this study, the efficacy and safety of two nilotinib doses, 300 mg twice...
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University of California at Los Angeles Dept. of Hematology Clinic
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Myeloid Derived Suppressor Cells and Chronic Myeloid Leukemia NA The suppression of the immune system creates a permissive environment for d...
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Multiple Locations
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Study of Treatment With Nilotinib in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase PHASE4 Maintain and monitor long-term hematological and cytogenetic responses prev...
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Novartis Investigative Site
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Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients N/A The purpose of this prospective, single-institution observational study is ...
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A Study of AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit Mutation PHASE2 The purpose of this study is to determine whether nilotinib is efficacious ...
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City of Hope National Medical Center City of Hope national Med Ctr
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Study Assessing Deep Molecular Response in Adult Patients With CML in Chronic Phase Treated With Nilotinib Firstline. PHASE4 The main purpose of this study was to evaluate the rate of deep molecular r...
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Novartis Investigative Site
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Study of Platelet Derived Growth Factor Receptor (PDGFR) in Recurrent Malignant Gliomas PHASE2 The purpose of this study is to determine the survival, disease response, a...
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The Rebecca and John Moores UCSD Cancer Center
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High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia NA This pilot clinical trial studies the feasibility of choosing treatment bas...
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Fred Hutch/University of Washington Cancer Consortium
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Effect of Nilotinib in Cerebellar Ataxia Patients PHASE2 This is an institutional cohort study. Patients confirmed with spinocerebel...
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Seoul National University Hospital
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Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma PHASE2 Background:
Advanced urothelial cancer has no cure. But only a few chemoth...
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National Institutes of Health Clinical Center
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