Found 123 matching trials
A Study of Imatinib Versus Nilotinib in Adult Patients With Newly Diagnosed Philadelphia Chromosome Positive (Ph+) Chronic Myelogenous Leukemia in Chronic Phase (CML-CP) PHASE3 In this study, the efficacy and safety of two nilotinib doses, 300 mg twice...
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University of California at Los Angeles Dept. of Hematology Clinic
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Myeloid Derived Suppressor Cells and Chronic Myeloid Leukemia NA The suppression of the immune system creates a permissive environment for d...
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Multiple Locations
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Study of Treatment With Nilotinib in Adult Patients With Imatinib - Resistant or - Intolerant Chronic Myeloid Leukemia in Blast Crisis, Accelerated Phase or Chronic Phase PHASE4 Maintain and monitor long-term hematological and cytogenetic responses prev...
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Novartis Investigative Site
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Precision Dosing of Tyrosine Kinase Inhibitors in CML Patients N/A The purpose of this prospective, single-institution observational study is ...
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High Throughput Drug Sensitivity Assay and Genomics- Guided Treatment of Patients With Relapsed or Refractory Acute Leukemia NA This pilot clinical trial studies the feasibility of choosing treatment bas...
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Fred Hutch/University of Washington Cancer Consortium
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Genomic Based Assignment of Therapy in Advanced Urothelial Carcinoma PHASE2 Background:
Advanced urothelial cancer has no cure. But only a few chemoth...
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National Institutes of Health Clinical Center
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Nilotinib Plus Pegylated Interferon-α2b in CML PHASE2 The purpose of this trial is to assess the effect of switching CML patients...
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Aarhus University Hospital
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Efficacy of Nilotinib Versus Imatinib in Ph+ CML in Early CP Who Have a Suboptimal Molecular Response to Imatinib PHASE3 In this study, the efficacy of nilotinib at 400 mg BID will be compared wit...
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Seoul St. Mary's Hospital
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A Study of Imatinib and Nilotinib in Patients With Chronic Myelogenous Leukemia in Chronic Phase PHASE3 The extension study followed the core study CAMN107ECN02 (NCT01275196). whi...
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Novartis Investigative Site
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Study to Evaluate Nilotinib in Chronic Myelogenous Leukemia (CML) Patients With SubOptimal Response PHASE4 To evaluate the major molecular response (MMR) rate at 12 months of nilotin...
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Novartis Investigative Site
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