Found 36 matching trials
A Study in Healthy People to Test Whether Different Doses of BI 1015550 Have Potential to Induce Heart Rhythm Abnormalities PHASE1 The main objective of this trial is to evaluate the effects of a single the...
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Quotient Sciences
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A Study to Test How BI 1015550 is Taken up in the Blood of People With and Without Kidney Problems PHASE1 This study is open to adults aged 18 years and older. People without kidney...
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CRS Clinical Research Services Kiel GmbH
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Relative Bioavailability of BI 1015550 Following Oral Administration Under Fed and Fasted Conditions in Healthy Male Subjects PHASE1 The primary objective of this trial is to investigate the effect of food on...
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Humanpharmakologisches Zentrum Biberach
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A Study in Healthy Men to Test How Bosentan Influences the Amount of Nerandomilast in the Blood PHASE1 The main objective of this trial is to investigate the effect of bosentan, ...
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Humanpharmakologisches Zentrum Biberach
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This Study Evaluates the Safety, Target Engagement, and Preliminary Efficacy of Galunisertib (TGF-βR1/ALK5 Inhibitor)Combined With Nerandomilast (PDE4 Inhibitor) in GREM2-positive ALS, a Biomarker-defined Subgroup Hypothesized to Reflect Heightened TGF-β/SMAD-driven Astrocytic and Fibrotic Signaling PHASE2 Amyotrophic lateral sclerosis (ALS) is a relentlessly progressive neurodege...
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Multiple Locations
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A Study to Test How Different Doses of Nerandomilast (BI 1015550) Are Taken up in the Body of Healthy Japanese Men PHASE1 The main objectives of this trial are to investigate pharmacokinetics (PK) ...
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SOUSEIKAI Sumida Hospital
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A Study in Healthy Men to Find Out How BI 1015550 is Taken up and Handled by the Body PHASE1 The main objective of this trial is to investigate the basic pharmacokineti...
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A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood PHASE2 This study is open to adults with idiopathic pulmonary fibrosis (IPF) who a...
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Renovatio Clinical-The Woodlands-69551
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FIBRONEER-ACT: A Study to Test Whether Nerandomilast Helps People With Fibrosing Interstitial Lung Disease at Risk for Disease Progression PHASE3 This study is open to adults with fibrosing interstitial lung disease (ILD)...
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University of Alabama at Birmingham
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A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis PHASE3 This study is open to people aged 40 years or older who have at least 1 fam...
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University of California Los Angeles
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