Found 13 matching trials
Precision Medicine Approaches for Neoadjuvant Therapy in High-risk Sarcoma Patients N/A This is a cohort study aimed at developing a stratified medicine approach f...
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The Royal Marsden Hospital
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Hydralazine and Valproate Added to Chemotherapy for Breast Cancer PHASE2 Aberrant DNA methylation and histone deacetylation participate in cancer de...
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Instituto Nacional de Cancerologia
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A Platform Study of Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer EARLY_PHASE1 This is an open-label, non-randomized, exploratory platform protocol design...
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Cedars-Sinai Cancer at SOCC
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Zeprumetostat, Azacitidine Combined With Lipo-MIT in R/R PTCL PHASE2 This clinical trial is a Phase II study investigating the effectiveness and...
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The First Affiliated Hospital of Soochow University
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Pilot Study on Rutin Combined With Tislelizumab and GC (Gemcitabine and Cisplatin) as Neoadjuvant Therapy for Platinum-refractory Muscle-invasive Bladder Cancer PHASE1 This trial aims to evaluate the efficacy, safety, and biological mechanisms...
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First Affiliated Hospital of Chongqing Medical University
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Neoadjuvant Inhaled Azacytidine With Platinum-Based Chemotherapy and Durvalumab (MEDI4736) - a Combined Epigenetic-Immunotherapy (AZA-AEGEAN) Regimen for Operable Early-Stage Non-Small Cell Lung Cancer (NSCLC) PHASE1 Background:
Lung cancer is the leading cause of cancer-related death world...
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National Institutes of Health Clinical Center
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Biomarkers and Outcome Predictors of Pediatric Nephrotic Syndrome: A Genetic, Transcriptomic, and Secretome Multiomics Study N/A Idiopathic Nephrotic Syndrome is a rare disease of the kidneys, which typic...
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Multiple Locations
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Efficacy of Hypomethylating Agents vs. Intensive Chemotherapy in Acute Myeloid Leukemia Using 5hmC as a Blood-Based Minimal Residual Disease Marker PHASE2 This is a therapeutic intervention trial evaluating the clinical utility of...
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Houston Methodist Neal Cancer Center
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Multi-omics Sequencing in Neoadjuvant Immunotherapy of Gastrointestinal Tumors PHASE2 immunotherapy,gastric cancer,rectal cancer,biomark...
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Army Medical Center
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Epigenetics of TNBC in Overweight and Obese Hispanic & Non-Hispanic White Women N/A A key tenet of this project is that of reaching translational human diagnos...
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University of Arizona Cancer Center
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