Found 14 matching trials
Study of ABT-263 When Administered in Combination With Either Fludarabine/Cyclophosphamide/Rituximab or Bendamustine/Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia PHASE1 This is a Phase 1 study evaluating the safety of ABT-263 administered in co...
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Site Reference ID/Investigator# 17841
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Assess the Oral Bioavailability of a New ABT-263 Formulation in Healthy Female Subjects PHASE1 This is a Phase 1, randomized, open-label, single center, three period cros...
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Site Reference ID/Investigator# 23602
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A Study Evaluating Safety and Tolerability, and Pharmacokinetics of Navitoclax Monotherapy and in Combination With Ruxolitinib in Participants With Myeloproliferative Neoplasm PHASE1 There are 5 parts to this study for which the primary objectives are to eva...
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Active Not Recruiting
Location
City of Hope /ID# 239769
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A Phase 1b-2 Trial to Assess Venetoclax and Navitoclax Consolidation and Post-transplant Maintenance in High-risk Patients With T-ALL PHASE1 This is a national, multicenter, phase II clinical trial to evaluate the po...
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Soroka Medical Center
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A Study Evaluating ABT-263 With Erlotinib, ABT-263 With Irinotecan, and ABT-263 Monotherapy in Cancer Subjects PHASE1 This is a three arm study to determine the maximum tolerated dose (MTD) of ...
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Site Reference ID/Investigator# 37463
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Expanded Access Program of Venetoclax and Navitoclax for Pediatric Patients with Relapsed or Refractory ALL or LL N/A The overall goal of this expanded access program is to provide Venetoclax a...
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No Longer Available
Location
University of Texas Southwestern Medical Center
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HEM-iSMART-A: Decitabine / Venetoclax and Navitoclax in Pediatric Patients With Relapsed or Refractory Hematological Malignancies PHASE1 HEM-iSMART is a master protocol which investigates multiple investigational...
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Princess Máxima Center for Pediatric Oncology
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Navitoclax in Relapsed or Refractory High-Risk Myelodysplastic Syndrome PHASE1 This trial tests the safety, side effects, and best dose of navitoclax in c...
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Sidney Kimmel Cancer Center at Thomas Jefferson University
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A Study of Navitoclax in Addition to Bendamustine and Rituximab in Patients With Relapsed Diffuse Large B-Cell Lymphoma (NAVIGATE) PHASE2 This randomized, open-label, multicenter study will evaluate the efficacy a...
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Multiple Locations
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Combination Navitoclax, Venetoclax and Decitabine for Advanced Myeloid Neoplasms PHASE1 The purpose of this research study is to test the safety of a new three dru...
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Active Not Recruiting
Location
Brigham and Women's Hospital
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