Found 43 matching trials
The NIPA Study Naloxegol Administration to Prevent Opioids Induced Gastrointestinal Motility Disturbance in Brain Injured PAtients
PHASE3Impaired gastrointestinal transit (IGT) especially constipation, is common ...
Location
CHU de Bordeaux - Réanimation chirurgicale
Colonic Motor Patterns in Healthy Volunteers
PHASE4Characterization of motor patterns with opioid agonists (codeine) ingestion...
Naloxegol in Cancer Opioid-Induced Constipation
PHASE2The purpose of this study is to compare the effect of naloxegol versus the ...
Location
UCSD Moores Cancer Center
Absorption, Distribution, Metabolism and Excretion (ADME) Study With Single Oral Administration of [14C] NKTR-118
PHASE1Study to Assess the Absorption, Metabolism and Excretion of \[14C\] NKTR-11...
Study in Healthy Volunteers to Investigate the Effects of Rifampin on the Pharmacokinetics of NKTR-118
PHASE1Study in healthy volunteers to investigate the effects of Rifampin on the P...
Evaluation of Naloxegol in the Prevention of POI After Cystectomy
PHASE2Postoperative ileus (POI) is defined as a transient reduction of bowel moti...
Location
Multiple Locations
Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids
PHASE4This study evaluates the addition of naloxegol (Movantik) to a laxative pro...
Location
Tufts Medical Center
Risk of Major Adverse Cardiovascular Events for Naldemedine & Other Medications for Opioid Induced Constipation
N/AThe research objective is to characterize the risk of a major adverse cardi...
Single and Multiple Ascending Dose Study for NKTR-118 and Cross-over Study to Investigate the Effect of Food for NKTR-118 in Japanese Healthy Subjects
PHASE1The purpose of this study is to evaluate the safety and tolerability of NKT...
A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects
PHASE1The purpose of this study is to evaluate the effects on QTc interval in hea...