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A Bioavailability Study With Alternate Methods of Administration of Naloxegol Tablets, and Solution PHASE1 This clinical study is an open-label, randomized, 4-period, 4-treatment, cr...
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Effect of Naloxegol on Postoperative Ileus in Patients Undergoing Cardiac Surgery PHASE3 Postoperative ileus, defined as the transient postoperative functional inhi...
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CMC Ambroise Paré
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Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids PHASE4 This study evaluates the addition of naloxegol (Movantik) to a laxative pro...
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Tufts Medical Center
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Naloxegol for the Prevention of Constipation in Postoperative Spinal Surgery Patients PHASE4 Constipation is a known complication of the postoperative period after spin...
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Massachusetts General Hospital
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Methylnaltrexone vs Naloxegol in the Treatment of Opioid-Induced Constipation PHASE4 The purpose of this study is to compare the efficacy of subcutaneous versus...
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A 12-week Extension of the Phase III Study (D3820C00004) to Assess the Effect and Safety of NKTR-118 in Patients With Non-cancer-related Pain and Opioid-induced Constipation PHASE3 The purpose of this study is to evaluate the effect and safety of NKTR-118 ...
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A Placebo-controlled Four Way Crossover Study to Asses the Effect of a Single Oral Dose of NKTR-118 on QTc Interval in Healthy Male Subjects PHASE1 The purpose of this study is to evaluate the effects on QTc interval in hea...
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