Found 10 matching trials
To Evaluate the Safety of Long-term Use of HPN-100 in the Management of Urea Cycle Disorders (UCDs) PHASE4 This was an open-label, long-term safety study of HPN-100 (RAVICTI; glycero...
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UCLA Pediatrics/Genetics
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Arginine and Buphenyl in Patients With Argininosuccinic Aciduria (ASA), a Urea Cycle Disorder PHASE2 Urea cycle disorders are inherited illnesses in which the body does not pro...
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Baylor College of Medicine
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Study of Glycerol Phenylbutyrate & Sodium Phenylbutyrate in Phenylbutyrate Naïve Patients With Urea Cycle Disorders (UCDs) PHASE4 This is a randomized, controlled, open-label parallel arm study to assess t...
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University of Florida (UF) - Shands Hospital
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Dose-Escalation Safety Study of HPN-100 to Treat Urea Cycle Disorders PHASE2 The purpose of this study is to determine whether HPN-100 is safe and toler...
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University of Minnesota
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Study of the Safety, Pharmacokinetics and Efficacy of HPN-100, in Pediatric Subjects With Urea Cycle Disorders (UCDs) PHASE3 This non-randomized, open-label study was approximately one year in duratio...
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UCLA Pediatrics/Genetics
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A Study of Glyceryl Tri-(4-phenylbutyrate) (GT4P) PHASE1 To determine the safety and tolerability of single oral doses of HPN-100 as...
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Medical Sanitary Division #2
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Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD) PHASE3 This was a long-term safety study HPN-100 in urea cycle disorder (UCD) subj...
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Long Beach Memorial
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Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders PHASE3 This was a randomized, active-controlled, double-blind, cross-over study de...
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Long Beach Memorial
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Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders PHASE2 Protocol HPN-100-005 was the first study of HPN-100 in pediatric subjects w...
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A Study of Glyceryl Tri-(4-phenylbutyrate) Administered Orally as a Single Dose, and Twice Daily for Seven Consecutive Days to Subjects With Hepatic Impairment With Cirrhosis and to a Control Group PHASE1 The purpose of this study is to determine the safety and tolerability of GT...
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National University of Pharmacy
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