Found 34 matching trials
Autologous T Cells and Cyclophosphamide in Treating Patients With Soft Tissue Sarcoma That is Metastatic or Cannot Be Removed By Surgery PHASE1 This phase I trial studies the side effects and how well giving autologous ...
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Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium
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CT Antigen TCR-redirected T Cells for Ovarian Cancer. PHASE1 This study, will take a subject's "T cells" and "teach" them to be able to ...
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City of Hope National Medical Center
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Genetically Engineered Cells (NY-ESO-1 TCR Engineered T Cells and HSCs) After Melphalan Conditioning Regimen in Treating Patients With Recurrent or Refractory Ovarian, Fallopian Tube, or Primary Peritoneal Cancer PHASE1 This phase I trial studies the best dose and side effects of NY-ESO-1 T cel...
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Roswell Park Cancer Institute
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NY-ESO-1-Specific T-cells in Treating Patients With Advanced NY-ESO-1-Expressing Sarcomas Receiving Palliative Radiation Therapy PHASE1 This pilot, phase I trial studies the safety of cancer-testis antigen (NY-E...
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Fred Hutch/University of Washington Cancer Consortium
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Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors PHASE2 This trial will evaluate safety and efficacy of human engineered T-cell the...
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Active Not Recruiting
Location
City of Hope National Medical Center
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Clinical Trial of Safety, Tolerability and Antitumor Activity of Genetically Engineered T Cells in Combination With Anti-Cancer Agents in Relapsed and Refractory Synovial Sarcoma Expressing New York Esophageal Antigen-1 (NY-ESO-1) and/or LAGE-1a PHASE2 Adoptive T-cell therapy is a therapeutic approach that aims to generate an ...
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Multiple Locations
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Study of TBI-1301 (NY-ESO-1 Specific TCR Gene Transduced Autologous T Lymphocytes) in Patients With Solid Tumors PHASE1 The target populations for this phase I study with TBI-1301 are patients wi...
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Active Not Recruiting
Location
Princess Margaret Cancer Centre
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Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1 PHASE1 The goal of this clinical research study is to find a recommended dose of d...
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MD Anderson Cancer Center
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Genetically Modified T Cells and Decitabine in Treating Patients With Recurrent or Refractory Ovarian, Primary Peritoneal, or Fallopian Tube Cancer PHASE1 This phase I trial studies the side effects of genetically modified T cells...
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Active Not Recruiting
Location
Roswell Park Cancer Institute
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Letetresgene Autoleucel Engineered T Cells Alone and in Combination With Pembrolizumab in NY-ESO-1 Positive Multiple Myeloma PHASE1 This trial will evaluate safety, tolerability, and efficacy of letetresgene...
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GSK Investigational Site
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