Found 30 matching trials
A Study to Evaluate the Efficacy, Safety and Pharmacokinetics of Emapalumab in Adult Patients With HLH PHASE2 Hemophagocytic lymphohistiocytosis (HLH) is a rare, life-threatening condit...
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MD Anderson Cancer Center
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Dose-modified Emapalumab and Ruxolitinib (E-Ru) Regimens for Hemophagocytic Lymphohistiocytosis PHASE2 This study is trying to evaluate the efficacy and safety of dose-modified E...
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The First Affiliated Hospital of Soochow University
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A Study of Emapalumab for Pediatric Aplastic Anemia PHASE2 The purpose of this study is to find out whether upfront emapalumab treatme...
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Memorial Sloan Kettering Cancer Center (All Protocol Activities)
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Randomized Stepped Wedge Study of Emapalumab in APECED Enteritis PHASE2 Background:
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy...
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National Institutes of Health Clinical Center
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GTP Regimen in the Treatment of Refractory/Recurrent HLH PHASE3 The goal of this clinical trial is to learn about efficacy and safety of GT...
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Multiple Locations
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Emapalumab Treatment For Anticipated Clinical Benefit In Sepsis Driven By The Interferon-Gamma Endotype (The EMBRACE Trial) PHASE2 EMBRACE is a double-blind, randomized, placebo-controlled, phase IIa study ...
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Active Not Recruiting
Location
1st Department of Internal Medicine, Thriasio Elefsis General Hospital
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First in Human Study of an Anti-IFN Gamma Monoclonal Antibody in Healthy Volunteers PHASE1 The purpose of this study is to determine the safety, pharmacodynamic and p...
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Emapalumab With Post-Transplant Cyclophosphamide, Tacrolimus and Mycophenolate Mofetil for the Prevention of Graft-versus-Host Disease After Donor Reduced-Intensity Hematopoietic Cell Transplant PHASE1 This phase I trial tests the safety, side effects and effectiveness of emap...
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City of Hope Medical Center
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Study to Investigate Safety, Efficacy of an Anti-IFNγ mAb in Children With Primary Haemophagocytic Lymphohistiocytosis PHASE2 The purpose of this study is to assess the safety, tolerability and efficac...
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Children's Hospital Colorado
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A Post-authorization Study to Describe the Safety and Efficacy of Emapalumab for the Treatment of pHLH in Treatment Experienced Chinese Patients PHASE4 The goal of this post-authorization study is to describe safety and efficac...
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Swedish Orphan Biovitrum Research site
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