Found 9 matching trials
Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation PHASE2 This will be a double-blind, randomized, placebo-controlled, parallel group...
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University of Alabama
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PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study PHASE2 The primary objective of this study is to evaluate several interventions gi...
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Mayo Clinic Scottsdale
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A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multicenter Study to Evaluate the Efficacy and Safety of Cavosonstat Administered Twice Daily Compared With Placebo for 24 Weeks in Adult Subjects With Chronic Obstructive Pulmonary Disease (COPD) PHASE2 Brief Summary: The purpose of this study is to to evaluate the efficacy and...
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Multiple Locations
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Study of Cavosonstat (N91115) in CF Patients Who Are Heterozygous for F508del-CFTR and a Gating Mutation and Being Treated With Ivacaftor PHASE2 Cavosonstat (N91115) is being studied as a potential novel therapy for cyst...
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National Jewish Health
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MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetics of Cavosonstat (N91115) in Healthy Subjects (SNO-9) PHASE1 The present study is designed to assess the safety and tolerability of esca...
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DaVita Clinical Research
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MAD Study Evaluating the Safety, Tolerability, and Pharmacokinetic Effects of N91115 in Healthy Subjects PHASE1 A study in healthy subjects to assess the safety, tolerability, and pharmac...
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DaVita Clinical Research
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Study of N91115 in Patients With Cystic Fibrosis Homozygous F508del-CFTR Mutation PHASE1 This Phase 1b study in F508del-CFTR homozygous CF patients is being conduct...
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University of Alabama @ Birmingham
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PK Study of N91115 in Cystic Fibrosis Patients PHASE1 This Phase 1 study in F508del-CFTR homozygous CF patients is being conducte...
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University of Alabama @ Birmingham
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A Drug-Drug Interaction Study of N91115 +/- Rifampin in Healthy Adult Subjects PHASE1 The present study is designed to assess the effects of Rifampin on the phar...
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St. Anthony's Medical Plaza 1
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