Found 8 matching trials
Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive Disorder
PHASE2Background:
\- Drugs and talk therapy help treat depression, but these tre...
Location
National Institutes of Health Clinical Center, 9000 Rockville Pike
Acute Glycine Pharmacodynamic Study
NAThe purpose of this study is to use proton magnetic resonance spectroscopy ...
Location
McLean Imaging Center, McLean Hospital
GlyT-1 Inhibitor Treatment for Refractory Schizophrenia
PHASE2The etiology of schizophrenia remains unclear In recent one decade, hypofun...
Location
China Medical University Hospital
Efficacy & Safety of SCH 900435 in Schizophrenia (Study P06079)(WITHDRAWN)
PHASE2The purpose of this study is to assess whether SCH 900435 (Org 25935) 16 mg...
Location
Multiple Locations
Safety, Tolerability, PK of Oral NYX-2925 in Healthy Volunteers
PHASE1This is a first in human study of NYX-2925. It will evaluate single and mul...
Location
Spaulding Clinical
N-methyl Glycine (Sarcosine) for the Treatment of Obsessive Compulsive Disorder (OCD)
PHASE2Several lines of evidence implicate glutamatergic dysfunction in the pathop...
Location
China Medical University Hospital
Treatment of N-methyl-D-aspartate (NMDA) Enhancers for Schizophrenia
PHASE2Hypofunction of N-methyl-D-aspartate (NMDA) receptor has been implicated in...
Location
Changhua Hospital
Adjuvant Treatment With a Glycine Uptake Inhibitor in Participants With Negative Symptoms of Schizophrenia (P05695) (MK-8435-001)
PHASE2The purpose of this study is to determine whether MK-8435 (Org 25935) is mo...
Location
Multiple Locations