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Haploidentical Transplant for People With Chronic Granulomatous Disease (CGD) Using Alemtuzumab, Busulfan and TBI With Post-Transplant Cyclophosphamide EARLY_PHASE1 Background:
CGD causes infections and inflammation. The only cure currentl...
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Location
National Institutes of Health Clinical Center
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A Trial of Plerixafor/G-CSF as Additional Agents for Conditioning Before TCR Alpha/Beta Depleted HSCT in WAS Patients PHASE2 Treatment Study to assess of safety and efficiency of conditioning with Ple...
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Dmitry Rogachev Federal Research and Clinical Centre of Paediatric Haematology, Oncology and Immunology
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Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer PHASE1 This clinical trial will evaluate the safety and activity of mutant KRAS G1...
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Changhai Hospital
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Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Advanced Hematologic Cancer PHASE1 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cel...
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Multiple Locations
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High-Dose 3F8/GM-CSF Immunotherapy Plus 13-Cis-Retinoic Acid for Consolidation of First Remission After Myeloablative Therapy and Autologous Stem-Cell Transplantation PHASE2 The purpose of this study is to see if high-dose 3F8 combined with GM-CSF i...
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Memorial Sloan-Kettering Cancer Center
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Intentional Rejection of the Donor Graft Using Recipient Leukocyte Infusion(s) Following Nonmyeloablative Allogeneic Stem Cell Transplant PHASE1 The proposed study is based on our observation of paradoxical tumor regress...
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Massachusetts General Hospital
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Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD) PHASE3 This is a single-dose, open-label study in pediatric participants with seve...
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Active Not Recruiting
Location
Levine Children's Hospital - Hematology
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Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma PHASE3 This randomized phase III trial compares two different high-dose chemothera...
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Children's Hospital of Alabama
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Phase I Study of Autologous Tumor-Draining Lymph Node-Derived Lymphocytes for Advanced HER2-Negative Breast Cancer PHASE1 RATIONALE: Patients with HER2-negative advanced breast cancer have limited ...
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Sun Yat-sen Memorial Hospital, Sun Yat-sen University
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CAR T Cell Receptor Immunotherapy Targeting VEGFR2 for Patients With Metastatic Cancer PHASE1 Background:
The National Cancer Institute (NCI) Surgery Branch has develop...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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