Found 10 matching trials
Evaluating Premedication Regimens (Methylprednisolone vs Dexamethasone-based) for the Prevention of Systemic and Injection Site Reactions to Motixafortide in Patients With Multiple Myeloma Undergoing Stem Cell Mobilization, PARADE Trial PHASE4 This phase IV trial compares the effect of premedication regimens with meth...
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Emory University Hospital/Winship Cancer Institute
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Study to Investigate the Effect of BL-8040 (Motixafortide) on the QTc Interval in Healthy Subjects PHASE1 The study will assess the corrected QT (QTc) effects (electrocardiogram \[E...
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Chemo4METPANC Combination Chemokine Inhibitor, Immunotherapy, and Chemotherapy in Pancreatic Adenocarcinoma PHASE2 The purpose of this study is to determine if combination treatment with cem...
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Columbia University Irving Medical Center
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Motixafortide and Natalizumab to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD) PHASE1 Hematopoietic stem cell (HSC)-based gene therapies now offer curative poten...
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Washington University School of Medicine
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Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients PHASE3 This is a randomized, double-blinded, placebo-controlled, multi-center phas...
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Peking University People's Hospital
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A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization PHASE1 This study includes extended CD34+ profiling on the apheresis product of mu...
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Washington University School of Medicine
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SCD Stem Cell Mobilization and Apheresis Using Motixafortide PHASE1 This study is being done to see if the study drug, motixafortide, is safe i...
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University of Alabama at Birmingham
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Motixafortide for MRD Sensitization in AML PHASE2 This is a pilot phase I study evaluating the effect of motixafortide on det...
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Washington University School of Medicine
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Gene Editing For Sickle Cell Disease PHASE1 This study is being done to test the safety of a new treatment called gene ...
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St. Jude Children's Research Hospital
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Safety, Tolerability and Efficacy of the BL-8040 and Atezolizumab for Maintenance Treatment in Subjects With Acute Myeloid Leukemia (AML) PHASE1 A Phase Ib/II, Multicenter, Single Arm, Open-Label Study, To Evaluate the S...
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The University of Texas - Md Anderson Cancer Center - Leukemia Center
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