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Trial of Devimistat in Combination With Modified FOLFIRINOX in Patients With Metastatic Adenocarcinoma of the Pancreas PHASE1 This protocol will enroll patients with metastatic pancreatic cancer to rec...
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Rogel Cancer Center
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A Phase 1/2a Study of IMM-1-104 in Participants With Advanced or Metastatic Solid Tumors PHASE1 This is an open-label, dose-exploration and expansion study to determine th...
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Active Not Recruiting
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NeoOPTIMIZE: Early Switching of mFOLFIRINOX or Gemcitabine/Nab-Paclitaxel Before Surgery for the Treatment of Resectable, Borderline Resectable, or Locally-Advanced Unresectable Pancreatic Cancer PHASE2 This phase II trial evaluates whether early switching from modified fluorou...
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Active Not Recruiting
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OHSU Knight Cancer Institute
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Adapted Guided Stereotactic Body Radiotherapy Combined With Chemotherapy and Enhancement of Novel Drug Ivonescimab for Pancreatic Cancer (ASCEND) PHASE1 This study aims to evaluate the safety and efficacy of Ivonescimab, a bispe...
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Shandong Cancer Hospital and Institute
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CPI-613 (Devimistat) in Combination With Modified FOLFIRINOX Plus Bevacizumab in Patients With Metastatic Colorectal Cancer PHASE1 Pre-clinical in vitro and in vivo data as well as early phase 1 clinical tr...
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Multiple Locations
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Platform Study of Circulating Tumor DNA Directed Adjuvant Chemotherapy in Colon Cancer (KCSG CO22-12) PHASE3 This study is a prospective, open-label, randomized phase 3 clinical trial....
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Dong-A University Hospital
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Tumor Subtypes in Subjects on FOLFIRINOX With Non-Metastatic Pancreatic Cancer PHASE2 This is a research study to evaluate how the genetic makeup of Pancreatic D...
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University of North Carolina at Chapel Hill Lineberger Comprehensive Cancer Center
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Combination of Anti-PD-1 Antibody and Chemotherapy in Metastatic Pancreatic Cancer PHASE2 The prognosis of pancreatic cancer is extremely poor. NCCN guidelines recom...
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the First Affiliated Hospital, School of Medicine, Zhejiang University
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GLP-1 RA Plus SOC Treatment in First-line, Metastatic Pancreatic, Colorectal, or Hepatocellular Cancer EARLY_PHASE1 There is a growing number of patients diagnosed with gastrointestinal cance...
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University of Arizona Cancer Center
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Utility of ctDNA in Early Switch of First-line mFOLFIRINOX in Metastatic Pancreatic Ductal Adenocarcinoma PHASE2 The purpose of this study is to understand whether a blood-based test calle...
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University of Miami
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