A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Regularly Transfused, Followed by a 5-Year Extension Period
PHASE3
ACTIVATE-KidsT (AG348-C-022) is a multicenter study designed to evaluate th...
A Study to Evaluate the Efficacy and Safety of Mitapivat in Pediatric Participants With Pyruvate Kinase Deficiency (PKD) Who Are Not Regularly Transfused, Followed by a 5-Year Extension Period
PHASE3
Study ACTIVATE-Kids (AG348-C-023) will evaluate the efficacy and safety of ...
Study to Evaluate the Effect of Multiple Doses of Itraconazole and Rifampin on the Single-Dose Pharmacokinetics of Mitapivat Sulfate (AG-348) in Healthy Adult Participants
PHASE1
Part 1 of this study will determine the effect of multiple-dose itraconazol...
A Study to Determine the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of AG-348 in Adult Participants With Non-transfusion-dependent Thalassemia
PHASE2
Study AG348-C-010 is a multicenter study to evaluate the efficacy, safety, ...