Found 12 matching trials
Food Effects on Milademetan Pharmacokinetics in Healthy Participants
EARLY_PHASE1The primary objectives of this trial are:
* To evaluate the effect of a hi...
Location
Covance Clinical Research Unit, Inc.
Milademetan Tosylate and Low-Dose Cytarabine With or Without Venetoclax in Treating Participants With Recurrent or Refractory Acute Myeloid Leukemia
PHASE1This phase I/II trial studies the side effects and best dose of milademetan...
Location
M D Anderson Cancer Center
Milademetan in Combination With Atezolizumab in Patients With Advanced Solid Tumors With CDKN2A Loss
PHASE1This is an open-label, single-arm, Phase 1b/2 study designed to evaluate th...
Location
Multiple Locations
A Multiple Ascending Dose Study of Milademetan in Subjects With Advanced Solid Tumors or Lymphomas
PHASE1This will be a Phase 1, open-label study of milademetan to assess its safet...
Location
Karmanos Cancer Institute
Study of Milademetan in Japanese Patients With Relapsed or Refractory Acute Myeloid Leukemia (AML)
PHASE1This is a Phase 1, multicenter, open-label study to evaluate safety, tolera...
Location
Japanese Red Cross Narita Hospital
Milademetan in Advanced/Metastatic Solid Tumors
PHASE2Phase 2, multicenter, single-arm, open-label basket study designed to evalu...
Location
Stanford University Medical Center
Treatment of Milademetan Versus Trabectedin in Patient With Dedifferentiated Liposarcoma
PHASE3Randomized, multicenter, open-label, Phase 3 registration study designed to...
Location
Stanford Cancer Center
A Study of Milademetan Administration on Cardiac Repolarization in Healthy Subjects
PHASE1This will be a Phase 1, single-center, 2-part study in healthy subjects. Pa...
Location
Nucleus Network Melbourne
Milademetan Plus Quizartinib Combination Study in FLT3-ITD Mutant Acute Myeloid Leukemia (AML)
PHASE1Participants with AML that have gone into remission and come back (relapsed...
Location
Ronald Reagan Medical Center, UCLA
Pharmacokinetics (PK) Drug Interaction Study of Milademetan and Itraconazole or Posaconazole in Healthy Participants
EARLY_PHASE1This will be an open-label, randomized, 3-treatment, 2-period, 2-sequence s...
Location
Covance Clinical Research Unit, Inc.