Found 27 matching trials
Cocaine-Metyrapone Interaction Study - 1
PHASE1The purpose of this study is to examine the safety of two consecutive days ...
Location
Cincinnati VA Medical Center
Metyrapone for Mild Autonomous Cortisol Secretion (MACS)
PHASE2The purpose of this study is to find out whether the study drug, metyrapone...
Status
Active Not Recruiting
Location
Mayo Clinic Minnesota
Effects of the Addition of Metyrapone to Antidepressant Therapy in Depression With Dexamethasone Suppression Test Non-suppression.
PHASE4The hypothesis of a link between depression and Hypothalamic-Pituitary Axis...
Location
Hopitaux Universitares de Strasbourg
Antiglucocorticoid Augmentation of antiDepressants in Depression
PHASE3Depression is one of the most common mental health problems, with at least ...
Location
Stockton Affective Disorders Service
Diagnosis of Central Adrenal Insufficiency in Patients With Prader-Willi Syndrome
NAThe purpose of this study is to determine presence of central adrenal insuf...
Location
Nationwide Children's Hospital
Metyrapone Versus Osilodrostat in Patients With Metabolic Autonomous Cortisol Secretion (MACS)
PHASE4This study will compare the efficacy and safety of the two 11β-hydroxylase ...
Location
Laikon General Hospital
Single and Multiple Rising Dose Study of Safety and PK of Metyrapone/Oxazepam Combination (EMB-001)
PHASE1This is a study of EMB-001 (a combination of two FDA-approved drugs, metyra...
Location
Collaborative Neuroscience Network, LLC
Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance
PHASE4The purpose of this study is to examine the impact of timed cortisol releas...
Location
Sleep and Performance Research Center
The Role of Glucocorticoids to Maintain Energy Homeostasis During Starvation (Gluco-Starve)
EARLY_PHASE1In a randomized, cross-over study, 20 healthy volunteers will receive a blo...
Location
University Hospital Basel
A Study to Evaluate EMB 001 in Subjects With Cocaine Use Disorder
PHASE2EMB-001 is a combination of 2 drugs: the cortisol synthesis inhibitor, mety...
Location
Pacific Treatment and Research Center, Department of Psychiatry, University of California, San Diego, School of Medicine