Found 35 matching trials
Study Evaluating Subcutaneous MOA-728 for the Treatment of Opioid-Induced Constipation (OIC) in Subjects With Chronic Non-Malignant Pain
PHASE3The primary purpose of the protocol is to evaluate the safety, efficacy, an...
Location
Multiple Locations
Naloxone and Intravenous Methylnaltrexone Effects on Bladder Function
PHASE1This is a double-blind, randomized, study at a single clinical site investi...
Location
Progenics Pharmaceuticals, Inc.
Effect of Methylnaltrexone (MNTX) on Electrocardiogram (ECG) Parameters and Cardiac Repolarization
PHASE1This study will employ a single-center, randomized, double-blind parallel-g...
Location
Progenics Pharmaceuticals
Effect of Methylnaltrexone (Relistor) on Digestion and Tolerance to Tube Feeding in Patients Treated With Opiates
PHASE3It is hypothesized that using methylnaltrexone in addition to pain killer n...
Location
Hahnemann University Hospital
Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide
PHASE1This double-blind, randomized, two-cohort, placebo-controlled, parallel gro...
Location
Progenics Pharmaceuticals, Inc.
Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine
PHASE4Ticagrelor is associated with more prompt and potent antiplatelet effects c...
Location
University of Florida
Study of Methylnaltrexone (MNTX) for the Relief of Constipation
PHASE3To determine the efficacy of subcutaneous MNTX to relieve opioid-induced co...
Location
Progenics Pharmaceuticals, Inc.
Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention
PHASE2This randomized controlled trial will prospectively evaluate the clinical b...
Location
Ohio State University
A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients
PHASE3To test the effectiveness of MNTX in advanced illness subjects....
Location
Progenics Pharmaceuticals, Inc.
A Study of Oral Methylnaltrexone (MNTX) for the Treatment of Opioid-Induced Constipation (OIC) in Participants With Chronic, Non-Malignant Pain
PHASE3MNTX 3201 is a Phase 3, international, multicenter, randomized, double-blin...
Location
PRA International