Found 15 matching trials
Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone (MNTX) in Subjects With Impaired Renal Function
PHASE1This study is evaluating the Pharmacokinetics of MNTX in healthy control su...
Location
Progenics Pharmaceuticals, Inc.
Study of Pharmacokinetics, Safety and Tolerability of Intravenous Methylnaltrexone Bromide
PHASE1This double-blind, randomized, two-cohort, placebo-controlled, parallel gro...
Location
Progenics Pharmaceuticals, Inc.
Study of the Pharmacokinetics of Intravenous Administered 14C-MNTX
PHASE1This is an open-label, radiotracer study, to be conducted in healthy, norma...
Location
Progenics Pharmaceuticals, Inc.
Effect of Methylnaltrexone on the PK/PD Profiles of Ticagrelor in Patients Treated With Morphine
PHASE4Ticagrelor is associated with more prompt and potent antiplatelet effects c...
Location
University of Florida
A a Single Dose Efficacy Study in Inducing Laxation in Advance Illness Patients
PHASE3To test the effectiveness of MNTX in advanced illness subjects....
Location
Progenics Pharmaceuticals, Inc.
Pharmacokinetics and Bioavailability Comparison of Two Different Formulations of MNTX Tablets
PHASE1This was a single-center, double-blind, randomized, cross-over Phase 1 stud...
Location
Progenics Pharmaceuticals, Inc.
Compassionate Use Study of Methylnaltrexone
NAThis is an open label compassionate use study of subcutaneously administere...
Location
Progenics Pharmaceuticals, Inc.
Effect of Cimetidine on the Single-Dose PK of IV- Administered MNTX
PHASE1This open-label study assesses the single-dose pharmacokinetics of intraven...
Location
Progenics Pharmaceuticals, Inc.
Methylnaltrexone for Opioid-induced Constipation in Cancer Patients
PHASE2The purpose of this study is to evaluate the efficacy of methylnaltrexone i...
Location
Fletcher Allen Health Care
Pharmacokinetics, Safety, and Tolerability of Methylnaltrexone in Volunteers With Impaired Hepatic Function
PHASE1This is a multicenter, non-randomized, single-dose, parallel-group study. E...
Location
Progenics Pharmaceuticals, Inc.