Found 16 matching trials
Exploring the Immune Response to SARS-CoV-2 modRNA Vaccines in Patients With Secondary Progressive Multiple Sclerosis (AMA-VACC) PHASE4 The purpose of this study was to understand whether participants could moun...
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Novartis Investigative Site
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COVID-19 Vaccine Response in Treated MS Patients N/A The primary goal of this study is to assess the impact of the two major dis...
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Brigham MS Center
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Post-Authorization Safety Study for Assessment of Pregnancy Outcomes in Patients Treated With Mayzent N/A This study will utilize a prospective, observational, exposure cohort desig...
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Novartis Investigative Site
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Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis PHASE2 To assess the efficacy of Mayzent on microglia pathology in patients with a...
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University at Buffalo, Buffalo General Hospital
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Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS PHASE4 The DELIVER-MS study seeks to answer the question: Does early treatment wit...
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Active Not Recruiting
Location
University of Colorado-Anschutz Medical Campus
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Safety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS Patients PHASE3 To assess safety and tolerability of patients converting from approved Rela...
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Novartis Investigative Site
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Repurposing Siponimod for Alzheimer's Disease PHASE2 Collaboration with multiple sclerosis (MS) specialty colleagues led us to f...
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St. Joseph's Hospital and Medical Center
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Mayzent (Siponimod) Onboarding of Secondary Progressive Multiple Sclerosis (SPMS) Patients With MSGo N/A This study was a retrospective, non-interventional, longitudinal, descripti...
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Novartis Investigational Site
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Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial NA FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) tar...
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Active Not Recruiting
Location
University of Alabama at Birmingham
Treatments Being Tested
Natalizumab/natalizumab-sztn, Alemtuzumab, Ocrelizumab, Rituximab/rituximab-arrx/rituximab-abbs/rituximab-pvvr, Cladribine, Ofatumumab, Ublituximab-xiiy, Ocrelizumab and hyaluronidase-ocsq Glatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod Learn More & Join Trial
Impact of Mayzent on aSPMS Patients in a Long-term NIS in Italy N/A This is an observational, multicenter, single-arm, prospective study conduc...
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Novartis Investigative Site
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