Found 77 matching trials
A 2-part Study to Investigate the Effect of Macitentan in Healthy Male Participants PHASE1 The purpose of this study is to evaluate the effect of macitentan at steady...
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Clinical Pharmacology Unit
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Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH) PHASE3 Combination therapy in pulmonary arterial hypertension (PAH) has been the s...
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Providence Medical Foundation
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Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies N/A A surveillance of respiratory tract related adverse events in patients trea...
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Cardiovascular Associates, P.C.
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Clinical Study on Macitentan, RT and TMZ Concurrent Therapy Followed by Maintenance Macitentan and TMZ in Newly Diagnosed Glioblastoma PHASE1 This is a prospective, single-center, open-label, 3+3 dose escalation Phase...
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MD Anderson Cancer Center
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A Study of Two Macitentan Formulations in Healthy Adult Participants PHASE1 The purpose of this study is to evaluate the bioequivalence of macitentan o...
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A Study of Pulmonary Arterial Hypertension Participants Treated With Macitentan or Selexipag N/A The purpose of the study is to evaluate the change from baseline to 12 mont...
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Generale Regionale F. Miulli
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REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtension PHASE4 The study evaluates the effect of macitentan on right ventricular and hemod...
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Massachussetts General Hospital
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An Upcoming Clinical Study to Measure the Safety and Impact of a Drug Called Macitentan in Teenage and Adult Fontan Patients. PHASE3 The aim of this open-label (OL) trial is to study the long-term use of maci...
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Massachusetts General Hospital Heart Center
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A Clinical Study to Find Out if Macitentan is Effective and Safe in Japanese Patients With Chronic Thromboembolic Pulmonary Hypertension (CTEPH). PHASE3 The endothelin receptor antagonist macitentan showed significant improvemen...
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Fukuoka University Nishijin Hospital
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Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument PHASE3 SYMPHONY is prospective, multi-center, open-label, single-arm, Phase 3b psy...
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Cardiovascular Associates of the Southeast, LLC
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