Found 22 matching trials
A Study of BMS-986466 With Adagrasib With or Without Cetuximab in Participants With Kirsten Rat Sarcoma Virus Glycine 12 to Cysteine (KRAS G12C)-Mutant Solid Tumors PHASE1 The purpose of this study is to find a safe, tolerable, and efficacious dos...
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Local Institution - 0047
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Adagrasib in Combination With Nab-Sirolimus in Patients With Advanced Solid Tumors and Non-Small Cell Lung Cancer With a KRAS G12C Mutation (KRYSTAL -19) PHASE1 This study will evaluate the safety, MTD and/or RP2D, PK, and clinical acti...
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Local Institution - 019-104
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Bioequivalence Study Between Adagrasib Reference Tablets and High Drug Load Tablets PHASE1 This is a study to evaluate bioequivalence between adagrasib reference tabl...
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Local Institution - 0003
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A Study to Assess the Pharmacokinetics, Safety and Tolerability of Single-dose Adagrasib (BMS-986503) in Healthy Participants of Japanese Descent PHASE1 The aim of this study is to assess the pharmacokinetics, safety and tolerab...
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CenExel ACT (Formerly Anaheim Clinical Trials; LLC)
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A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway PHASE1 This is a Phase 1, open-label, multicenter, study evaluating the safety, to...
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Local Institution - 001-108
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Genetic Testing in Guiding Treatment for Patients With Brain Metastases PHASE2 This phase II trial studies how well genetic testing works in guiding treat...
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Active Not Recruiting
Location
Anchorage Associates in Radiation Medicine
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The Clinical Trial to Evaluate the Pharmacokinetics and Safety of MRTX849 in Patients With Advanced Solid Tumors PHASE1 This is a phase 1, open-label, single-arm study in Chinese patients with un...
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Beijing Cancer Hospital
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Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21) PHASE2 This study will evaluate the efficacy of two dosing regimens of adagrasib (...
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Active Not Recruiting
Location
Local Institution - 101
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Phase 3 Study of MRTX849 (Adagrasib) vs Docetaxel in Patients With Advanced Non-Small Cell Lung Cancer With KRAS G12C Mutation PHASE3 This Phase 3 study will evaluate the efficacy of the investigational agent ...
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Active Not Recruiting
Location
Local Institution - 012-898
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Phase Ib Trial of the KRASG12C Inhibitor Adagrasib (MRTX849) in KRAS G12C Mutant Metastatic Pancreatic Cancer Patients PHASE1 To learn if the investigational study drug, adagrasib (also called MRTX849)...
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M D Anderson Cancer Center
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