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Alisertib and Fulvestrant in Treating Patients With Hormone Receptor Positive Breast Cancer That is Metastatic or Locally Advanced and Cannot Be Removed by Surgery PHASE1 This phase I trial studies the side effects and best dose of alisertib when...
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MLN8237 for a Subject With Adenocarcinoma of the Prostate N/A To allow a patient continued access to MLN8237...
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No Longer Available
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Multiple Locations
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Alisertib in Combination With Osimertinib in Metastatic EGFR-mutant Lung Cancer PHASE1 This phase I/Ib trial studies the side effects and best dose of alisertib w...
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University of California, San Francisco
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Study of MLN8237 in Participants With Advanced Hematological Malignancies PHASE1 This is an open-label, multicenter, phase 1 study of MLN8237 in participant...
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Multiple Locations
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Mass Balance, Pharmacokinetics and Metabolism Study of Alisertib PHASE1 The purpose of this study is to assess the mass balance (i.e. cumulative ex...
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Comprehensive Clinical Development
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Alisertib in Treating Patients With Relapsed or Refractory Peripheral T-Cell Non-Hodgkin Lymphoma PHASE2 This phase II trial studies how well alisertib works in treating patients w...
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Providence Hospital
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A Study MLN2480 in Combination With MLN0128 or Alisertib, or Paclitaxel, or Cetuximab, or Irinotecan in Adult Participants With Advanced Nonhematologic Malignancies PHASE1 The primary purpose of this study is to determine the safety profile and th...
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Massachusetts General Hospital Cancer Center
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A Phase I Clinical and Pharmacodynamic Study of MLN8237, A Novel Aurora A Kinase Inhibitor, in Participants With Advanced Malignancies PHASE1 This is a multicenter, dose escalation, phase 1 study of MLN8237 in adult p...
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Ciutat Sanitaria Vall d'Hebron - Servicio de Oncologia
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Alisertib and TAK-228 in Participants With Human Papilloma Virus (HPV) Associated Malignancies PHASE1 The goal of this clinical research study is to find the highest tolerable d...
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Multiple Locations
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Pharmacokinetics of Alisertib in Adults With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Function PHASE1 The purpose of this study is to evaluate the effect of moderate or severe h...
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Multiple Locations
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