Found 18 matching trials
Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001) PHASE1 The purpose of this study is to assess the efficacy, safety, and tolerabili...
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Active Not Recruiting
Location
Northwestern Memorial Hospital ( Site 0002)
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A Study of Calderasib (MK-1084) in KRAS Mutant Advanced Solid Tumors (MK-1084-001) PHASE1 This is a study evaluating the safety, pharmacokinetics, and efficacy of ca...
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Moffitt Cancer Center ( Site 0261)
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A Study of Calderasib (MK-1084) in Participants With Hepatic Impairment and Healthy Volunteers (MK-1084-017) PHASE1 The purpose of this study is to learn what happens to calderasib levels in ...
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Arizona Clinical Trials ( Site 0003)
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A Study of the Effect of Itraconazole and Phenytoin on Calderasib (MK-1084) in Healthy Adults (MK-1084-008) PHASE1 The goal of this study is to learn what happens to calderasib in a healthy ...
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Celerion (Site 0001)
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A Study to Evaluate the Effect of Food, Formulation, and a Proton Pump Inhibitor (PPI) on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-003) PHASE1 The purpose of this study is to evaluate the effect of food, formulation, a...
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Celerion (Site 0001)
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MK-3475A±Calderasib (MK-1084) in Completely Resected Stage IIA-IIIB (N2) KRAS G12Cm NSCLC (MK-1084-013) PHASE3 This is a phase 3, randomized, double-blind study of adjuvant calderasib pl...
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Instituto Alexander Fleming ( Site 0310)
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A Study to Evaluate the Effect of Formulation and Food on Calderasib (MK-1084) in Healthy Adult Participants (MK-1084-011) PHASE1 This study has 2 parts. Researchers want to learn what happens to calderasi...
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Celerion ( Site 0001)
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A Clinical Study of MK-1084 With Other Treatments for Non-small Cell Lung Cancer (MK-3475-01F) PHASE1 Researchers want to learn if MK-1084, the study medicine, can treat advance...
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Clermont Oncology Center ( Site 0041)
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A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016) PHASE1 Researchers want to learn about calderasib when given with rosuvastatin and...
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Celerion ( Site 0001)
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KEYMAKER-U01 Substudy 01J: A Study of Pembrolizumab Plus MK-1084 in Participants With Non-Small Cell Lung Cancer (NSCLC) With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) G12C Mutations (MK-3475-01J/KEYMAKER-U01J) PHASE2 Researchers want to learn if using a study medicine called MK-1084 can help...
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Clermont Oncology Center ( Site 0041)
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