Found 23 matching trials
A Phase II Trial of Ridaforolimus and Exemestane, Compared to Ridaforolimus, Dalotuzumab and Exemestane in Participants With Breast Cancer (MK-8669-064) PHASE2 The purpose of the study is to evaluate the efficacy of the triplet of rida...
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Multiple Locations
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Dose Escalation Trial of Dalotuzumab (MK-0646) in Advanced Solid Tumors and Multiple Myeloma (MK-0646-001) PHASE1 This study will look for the highest tolerated dose of dalotuzumab (MK-0646...
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Multiple Locations
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Trial of Fulvestrant, MK-0646, and Dasatinib for Metastatic Hormone Receptor-Positive HER2-Negative Breast Cancer PHASE1 The goals of this clinical research study are to learn the tolerable and ef...
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UT MD Anderson Cancer Center
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MK-0646, Etoposide, and Cisplatin in Treating Patients With Extensive-Stage Small Cell Lung Cancer PHASE1 RATIONALE: Monoclonal antibodies, such as MK-0646, can block tumor growth i...
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Juravinski Cancer Centre at Hamilton Health Sciences
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Phase I Study of Dalotuzumab (MK-0646) in Combination With Cetuximab and Irinotecan in Participants With Colorectal Cancer (MK-0646-016) PHASE1 The purposes of this study were to assess the safety, tolerability, pharmac...
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Multiple Locations
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Clinical and Translational Study of MK-0646 in Patients With Metastatic Neuroendocrine Tumors (NET) PHASE2 The purpose of this study is to test a new drug for neuroendocrine tumors. ...
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Memorial Sloan-Kettering at Basking Ridge
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A Study Evaluating Dalotuzumab (MK-0646) in Combination With Erlotinib for Participants With Non-Small Cell Lung Cancer (MK-0646-007) PHASE2 This is a Phase I/IIa study to evaluate safety and efficacy of dalotuzumab ...
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A Study of Ridaforolimus (MK-8669) in Combination With Dalotuzumab (MK-0646) Compared to Standard of Care Treatment in Estrogen Receptor Positive Breast Cancer Patients (MK-8669-041 AM3) PHASE2 This is a two-part study that will determine, if: 1) the combination of rid...
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Multiple Locations
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Phase I Imaging Study Evaluating Dalotuzumab (MK0646) in Combination With Erlotinib for Patients With Non-Small Cell Lung Cancer (MK-0646-008) PHASE1 This study will use imaging to look at tumor response to erlotinib (Part I)...
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Multiple Locations
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MK-0646 and Gemcitabine +/- Erlotinib for Patients With Advanced Pancreatic Cancer PHASE1 Objectives:
Primary Objectives:
* Phase I: Determine the maximal tolerate...
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University of Texas MD Anderson Cancer Center
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