Found 143 matching trials
Phase II Study Investigating the Combination of Encorafenib and Binimetinib in BRAF V600E Mutated Chinese Patients With Metastatic Non-Small Cell Lung Cancer PHASE2 This is a phase 2, multicenter, single-arm study with a safety lead-in to i...
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Beijing Cancer Hospital
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Safety and Oversight of the Individually Tailored Treatment Approach: A Novel Pilot Study NA This study is looking at outcomes in people with advanced cancers who have ...
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Peter MacCallum Cancer Centre
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Encorafenib and Binimetinib With or Without Nivolumab in Treating Patients With Metastatic Radioiodine Refractory BRAF V600 Mutant Thyroid Cancer PHASE2 This phase II trial studies how well encorafenib and binimetinib given with...
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Providence Portland Medical Center
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MEK Inhibitor 162 Relapsed and/or Refractory Acute Myeloid Leukemia (AML) and Poor Prognosis, Not Suitable for or Unwilling to Receive Standard Therapy PHASE1 The goal of Phase 1 of this clinical research study is to find the highest ...
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University of Texas MD Anderson Cancer Center
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Melanoma Metastasized to the Brain and Steroids PHASE2 This clinical trial is to clarify whether treatment with a checkpoint inhib...
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Herlev Universityhospital
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Adjuvant Encorafenib and Binimetinib in High-risk Stage II Melanoma With a BRAF Mutation. PHASE3 The purpose of the Columbus-AD study is to evaluate the efficacy and safety...
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Centro Oncologico Korben
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Prognostic and Treatment-Response Factors in Metastatic Melanoma: Multi-Center Analysis N/A This multicenter, retrospective observational study aims to identify clinic...
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Ankara Etlik City Hospital
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Binimetinib and Encorafenib for the Treatment of Metastatic Melanoma and Central Nervous System Metastases PHASE2 This phase II trial studies the effects of binimetinib and encorafenib in t...
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M D Anderson Cancer Center
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MEK162 in Healthy Subjects With Normal Hepatic Function and Subjects With Impaired Hepatic Function PHASE1 This study is a phase I, multi-center, open-label, single oral dose, parall...
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DaVita Clinical Research-Denver
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Binimetinib and Encorafenib for the Treatment of Pancreatic Cancer in Patients With a Somatic BRAF V600E Mutation PHASE2 This phase II trial studies the side effects and how well the combination o...
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Mayo Clinic in Arizona
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