Found 64 matching trials
T Cell Receptor Immunotherapy Targeting MAGE-A3 for Patients With Metastatic Cancer Who Are HLA-DP0401 Positive PHASE1 Background:
The National Cancer Institute (NCI) Surgery Branch has develop...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers PHASE1 The primary objectives of Phase 1A are to evaluate the safety of KITE-718, ...
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Banner MD Anderson Cancer Center
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Phase II Study to Assess the Safety and Immunogenicity of recMAGE-A3+AS15 ASCI With or Without Poly IC:LC PHASE2 The overall purpose of this research study is to find a better way to treat...
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H. Lee Moffitt Cancer Center and Research Institute
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Melanoma Vaccine With Peptides and Leuprolide PHASE2 The goal of this clinical research study is to learn if the drug leuprolide...
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UT MD Anderson Cancer Center
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Study of MAGE-A3 and NY-ESO-1 Immunotherapy in Combo With DTPACE Chemo and Auto Transplantation in Multiple Myeloma PHASE2 The hope is that the peptide vaccines will stimulate the immune system to a...
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University of Arkansas for Medical Sciences/MIRT
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Tumor Markers Study in Gastric Cancer for Cancer Immunotherapy (ONCO-RD 010 CRT) N/A Gastric cancer is one of the leading causes of cancer-related deaths worldw...
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Multiple Locations
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A Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their Tumor PHASE3 The purpose of this clinical trial is to evaluate the benefit of the immuno...
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GSK Investigational Site
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Study to Assess Safety and Immune Response of Stage IIB-IV Resected Melanoma After Treatment With MAGE-A3 ASCI EARLY_PHASE1 The goals of this study are to 1) assess the safety of recombinant MAGE-A3 ...
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University of Virginia
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Vaccine Therapy, Paclitaxel, and Carboplatin in Treating Patients Who Are Undergoing Surgery for Stage III or Stage IV Ovarian Cancer, Primary Peritoneal Cancer, or Fallopian Tube Cancer PHASE2 RATIONALE: Vaccines made from peptides may help the body build an effective...
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University of Virginia Cancer Center
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MG1-MAGEA3 With Ad-MAGEA3 and Pembrolizumab in Patients With Previously Treated Metastatic Melanoma or Cutaneous Squamous Cell Carcinoma PHASE1 This is a Phase 1b open-label dose escalation trial of Ad/MG1-MAGEA3 and Pe...
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Multiple Locations
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