Found 49 matching trials
Study of VX-809 in Cystic Fibrosis Subjects With the ∆F508-CFTR Gene Mutation PHASE2 The primary objective of the study was to evaluate the safety and tolerabil...
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Study of Cavosonstat (N91115) in Patients With CF Homozygous for the F508del-CFTR Mutation PHASE2 This will be a double-blind, randomized, placebo-controlled, parallel group...
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University of Alabama
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A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation PHASE4 The study will evaluate the impact of smart adherence technology for monito...
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Real-life Follow-up of Cystic Fibrosis Patients Treated With Ivacaftor+Lumacaftor (Orkambi*) N/A The purpose of the study is to examine the real-life safety and effectivene...
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Adult CF center, Service de Pneumologie, Cochin Hospital
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Lumacaftor/Ivacaftor Combination Therapy in Subjects With CF Who Have an A455E CFTR Mutation PHASE2 This is a Phase 2, randomized, double-blind, placebo-controlled, multicente...
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University Medical Center, Utrecht, Department of Pulmonology and Tuberculosis
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A Study of Lumacaftor in Combination With Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Who Are Homozygous for the F508del-CFTR Mutation PHASE3 The primary objective of the study was to evaluate the efficacy of lumacaft...
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Lum-Iva-biota: Exploring the Respiratory Mycobiota and Microbiota Profile in French CF Patients Taking Lumacaftor-Ivacaftor N/A n2015, VERTEX company - producing already KALYDECO (IVACAFTOR, VX-770) pote...
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CHU de Bordeaux - CRCM
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Phase 1, QT/QTC Interval Study in Healthy Subjects PHASE1 This study is designed to evaluate the effect of multiple doses of lumacaft...
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A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation PHASE2 The purpose of this study is to evaluate the safety and efficacy of treatme...
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Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease PHASE3 The purpose of this study is to evaluate the safety and tolerability of LUM...
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Multiple Locations
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