Found 37 matching trials
A Study to Evaluate the Safety,PK and PD of APG-2575 in Patients With Hematologic Malignancies
PHASE1The purpose of this study is to assess the safety, tolerability, pharmacoki...
Status
Active Not Recruiting
Location
Anhui Procincial hospital
APG-115 Alone or in Combination With APG-2575 in Recurrent or Refractory Neuroblastoma or Solid Tumors
PHASE1An open, non-randomized Phase Ib-II trial of dose-escalation and cohorts ex...
Location
Sun Yat-sen University Cancer Center
LME-Guided Precision Combination Therapy in B-cell Lymphoma Patients After CD19 CAR-T Failure
PHASE2This study evaluates a personalized treatment strategy for patients with la...
Location
Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai,
Pirtobrutinib, Lisaftoclax, and Rituximab in the Treatment of R/R DLBCL
PHASE2This study aims to evaluate the efficacy of combining pirtobrutinib, lisaft...
Location
The First Affiliated Hospital of Soochow University
A Study to Investigate the Safety, Tolerability, of APG-2575 as a Single Agent or in Combination for Breast Cancer
PHASE1This is a multi-center, open-label, phase Ib/II study of APG-2575 as a sing...
Location
Emory University Hospital
A Study of Lisaftoclax (APG-2575) Combined With Acalabrutinib Versus Immunochemotherapy for Newly Diagnosed CLL/SLL.
PHASE3This is a global, multicenter, randomized, open-label, Phase III confirmato...
Location
The First Affiliated Hospital of Bengbu Medical College
Study on the Treatment of Double/Triple-hit DLBCL With Chidamide and Lisaftoclax in Combination With Pola-R-CHP
PHASE2This is an open-label, multicenter clinical study for patients aged 65 and ...
Location
Multiple Locations
APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
EARLY_PHASE1This is a multi-center, single-agent, open-label, Phase I study of APG-2575...
Homoharringtonine, BCL-2 Inhibitor, Rituximab, and Prednisone in Relapsed/Refractory Diffuse Large B-Cell Lymphoma
PHASE1Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hod...
Location
Department of Hematology, The First Affiliated Hospital, School of Medicine, Zhejiang University
Global Trial in APG2575 for Patients With CLL/SLL
PHASE3This is a global multicenter, open label, randomized, registrational phase ...
Location
Ascentage Investigative Site