Found 162 matching trials
Effects of Vasopressors on Immune Response PHASE4 Noradrenaline is a catecholamine and the cornerstone treatment for the impr...
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Effects of Oxygen Status on Endotoxemia Induced Inflammation and Hypoxia Inducible Factor-1α PHASE1 Oxygen is a widely available gas that is cheap, easy to get and extensively...
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Intensive Care Medicine
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Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR N/A It is not known what causes Parkinson's disease and what makes it worsen ov...
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University of Exeter
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Immune Cell Response to Stimuli N/A This study will investigate the response of immune cells (neutrophils, mono...
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NIEHS Clinical Research Unit (CRU)
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Lipopolysaccharide (LPS) or Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Challenge Study on Healthy Subjects PHASE1 This exploratory study aims to assess exposure of healthy subjects to syste...
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GSK Investigational Site
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Development of Human Nasal Challenge Models With Microbial Constituents and Grass Pollen NA The investigators propose the development of a range of nasal spray challen...
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Imperial Clinical Respiratory Research Unit (ICRRU), St Mary's Hospital
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Phase 1a Study in Healthy Smokers to Investigate the Effect With MMI-0100 on Airway Inflammation in Induced Sputum After Challenge With Inhaled Lipopolysaccharide PHASE1 A Phase 1a, randomized, placebo controlled, two-way crossover study is to d...
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Respiratory Clinical Trials, The Heart Lung Centre
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A Prophylactic HIV Vaccine Trial to Evaluate the Safety and Immunogenicity of HIV Clade C DREP Alone and in Combination With a Clade C ENV Protein in Healthy HIV-uninfected Adults PHASE1 EHVA P01 is an international, phase I, prophylactic HIV vaccine trial to ev...
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Effect of Antioxidants on Oxygen Induced Vasoconstriction in Lipopolysaccharide (LPS) Induced Inflammatory Model in Humans NA Oxidative stress has been implicated in playing a pathogenic role in many d...
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Department of Clinical Pharmacology, Medical University of Vienna
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Inflammation and the Host Response to Injury (In Healthy Volunteers) PHASE1 The body's immune response to injury or infection is very complex.Endotoxin...
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