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🔬 Clinical Trials

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Trial Search

Current Search Criteria:

Intervention: Lipid Modifying Therapy (LMT)

Found 0 matching trials

Open Label Study of Long Term Safety Evaluation of Alirocumab

PHASE3

Primary Objective: To assess the long-term safety of alirocumab (SAR236553...

Status

Completed

Location

Investigational Site Number 840321

Start Date

2013-12-17

Trial ID

NCT01954394

Treatments Being Tested

Alirocumab Lipid-Modifying Therapy (LMT)

Study of Evinacumab (REGN1500) in Participants With Persistent Hypercholesterolemia

PHASE2

The primary objective of the study is to evaluate the reduction of LDL-C by...

Status

Completed

Location

Cedars-Sinai Medical Center

Start Date

2017-11-10

Trial ID

NCT03175367

Treatments Being Tested

Evinacumab Matching placebo Background Lipid Modifying Therapy (LMT)

Study of Alirocumab (REGN727/SAR236553) in Patients With heFH (Heterozygous Familial Hypercholesterolemia) Who Are Not Adequately Controlled With Their LMT (Lipid-Modifying Therapy)

PHASE3

This is a randomized, double-blind, placebo-controlled, parallel-group, mul...

Status

Completed

Location

Multiple Locations

Start Date

2012-12

Trial ID

NCT01709500

Treatments Being Tested

LMT (atorvastatin, simvastatin, or rosuvastatin)alirocumab Placebo

Phase III Study To Evaluate Alirocumab in Patients With Hypercholesterolemia Not Treated With a Statin (ODYSSEY CHOICE II)

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 840703

Start Date

2013-12-16

Trial ID

NCT02023879

Treatments Being Tested

Alirocumab Placebo (for Alirocumab)Non-statin LMT Diet Alone

Efficacy and Safety of Alirocumab Versus Usual Care on Top of Maximally Tolerated Statin Therapy in Patients With Type 2 Diabetes and Mixed Dyslipidemia (ODYSSEY DM-Dyslipidemia)

PHASE4

Primary Objective: To demonstrate the superiority of alirocumab in compari...

Status

Completed

Location

Investigational Site Number 840-163

Start Date

2016-03-15

Trial ID

NCT02642159

Treatments Being Tested

Alirocumab Statins Ezetimibe Fenofibrate Nicotinic acid Omega-3 fatty acids Antihyperglycemic Drug

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Placebo on Top of Lipid-Modifying Therapy in Patients With Heterozygous Familial Hypercholesterolemia (ODYSSEY HIGH FH)

PHASE3

Alirocumab (SAR236553/REGN727) is a fully human monoclonal antibody that bi...

Status

Completed

Location

Investigational Site Number 840742

Start Date

2012-06

Trial ID

NCT01617655

Treatments Being Tested

Alirocumab Placebo (for alirocumab)Lipid Modifying Therapy (LMT)

Efficacy and Safety Evaluation of Alirocumab in Patients With Heterozygous Familial Hypercholesterolemia or High Cardiovascular Risk Patients With Hypercholesterolemia on Lipid Modifying Therapy (ODYSSEY JAPAN)

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 392016

Start Date

2014-03

Trial ID

NCT02107898

Treatments Being Tested

Placebo (for alirocumab)Alirocumab Lipid-Modifying Therapy (LMT)

Study of Alirocumab (REGN727/SAR236553) in Patients With Primary Hypercholesterolemia and Moderate, High, or Very High Cardiovascular (CV) Risk, Who Are Intolerant to Statins (ODYSSEY ALTERNATIVE)

PHASE3

This is a randomized, double-blind, double-dummy, active-controlled, parall...

Status

Completed

Location

Multiple Locations

Start Date

2012-09-30

Trial ID

NCT01709513

Treatments Being Tested

Atorvastatin Ezetimibe Alirocumab Placebo

Evaluation of Alirocumab Versus Ezetimibe on Top of Statin in Asia in High Cardiovascular Risk Patients With Hypercholesterolemia

PHASE3

Primary Objective: To demonstrate the reduction of low-density lipoprotein...

Status

Completed

Location

Investigational Site Number 1560027

Start Date

2016-07-27

Trial ID

NCT02715726

Treatments Being Tested

Alirocumab Placebo for alirocumab ezetimibe placebo for ezetimibe atorvastatin rosuvastatin simvastatin

Efficacy and Safety of Alirocumab (SAR236553/REGN727) Versus Ezetimibe on Top of Statin in High Cardiovascular Risk Patients With Hypercholesterolemia (ODYSSEY COMBO II)

PHASE3

Alirocumab (SAR236553/REGN727) is a fully human monoclonal antibody that bi...

Status

Completed

Location

Investigational Site Number 840980

Start Date

2012-08

Trial ID

NCT01644188

Treatments Being Tested

Alirocumab Placebo (for alirocumab)Ezetimibe Placebo (for ezetimibe)Lipid Modifying Therapy (LMT)

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