Found 9 matching trials
Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN)
PHASE3This is a 2-part study in PBC participants with cholestatic pruritus and wi...
Location
GSK Investigational Site
Pharmacokinetics (PKs) and Metabolism of Radiolabelled Linerixibat
PHASE1Absorption, metabolism and excretion of linerixibat have been studied in pr...
Location
GSK Investigational Site
Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls
PHASE1This is a phase 1, open-label, single-dose study in adults with moderate he...
Location
GSK Investigational Site
Food Effect Study of Linerixibat Tablets in Healthy Adult Participants
PHASE1This study will evaluate the effect of food on the Pharmacokinetic (PK) and...
Location
GSK Investigational Site
Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Subjects
PHASE1In participants with inadequate response/intolerance to ursodeoxycholic aci...
Location
GSK Investigational Site
Dose Response Study of GSK2330672 for the Treatment of Pruritus in Participants With Primary Biliary Cholangitis
PHASE2This study is being conducted to evaluate the efficacy, safety and tolerabi...
Location
GSK Investigational Site
Linerixibat Compassionate Use for Cholestatic Pruritus Adult Patients With Primary Biliary Cholangitis (PBC)
N/AThe goal of this compassionate use program is to provide a mechanism to sup...
Location
Multiple Locations
Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants
PHASE1This study aims to investigate the effect of linerixibat on plasma concentr...
Location
GSK Investigational Site
Linerixibat Long-term Safety, and Tolerability Study
PHASE3This is an open-label, non-comparator, global, multi-center, long-term safe...
Status
Active Not Recruiting
Location
GSK Investigational Site