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Master Protocol to Assess the Safety and Antitumor Activity of Genetically Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Solid Tumors PHASE2 This trial will evaluate safety and efficacy of human engineered T-cell the...
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Active Not Recruiting
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City of Hope National Medical Center
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HIV Persistence in Lymph Node and Peripheral Blood N/A The aim of this project is to determine whether latent HIV is enriched in c...
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A Study of CC-98633, BCMA-targeted Chimeric Antigen Receptor (CAR) T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma PHASE1 This is a Phase 1, multicenter, open-label study of CC-98633, BCMA-Targeted...
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Local Institution - 103
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Peptide-Pulsed Dendritic Cell Vaccination in Combination With Nivolumab and Ipilimumab for the Treatment of Recurrent and/or Progressive Diffuse Hemispheric Glioma, H3 G34-mutant PHASE1 This phase I trial tests peptide-pulsed dendritic cell vaccination in combi...
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UCLA / Jonsson Comprehensive Cancer Center
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CHOEP + High Dose Therapy + Auto SCT for T-Cell Lymphoma PHASE2 The current standard of care for the frontline treatment of peripheral T-ce...
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Brigham and Women's Hospital
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Dose Exploration Study OF JWCAR129, BCMA-Targeted CART for RRMM PHASE1 This is an open-label, Phase 1 dose exploration study to evaluate the safet...
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First Affiliated Hospital, Soochow University
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Autologous Cells Derived Anti-CD19 CAR-Engineered T Cells With Concurrent BTK Inhibitor for B Cell Lymphoma PHASE3 This is a single-center, open-label and pragmatic clinical trial to evaluat...
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Union Hospital, Huazhong University of Science and Technology
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Sipuleucel-T With Immediate vs. Delayed Cytotoxic T-Lymphocyte-Associated Protein 4 (CTLA-4) Blockade for Prostate Cancer PHASE2 The purpose of this study is to find out what effects taking ipilimumab, as...
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University of California San Francisco
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Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma PHASE1 This phase I trial tests the safety and side effects of B-cell activating f...
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City of Hope Medical Center
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A Phase I/II Safety and Tolerability Dose Escalation Study of Autologous Stem Cells to Patients With Liver Insufficiency PHASE1 This is a prospective dose escalation study of the administration of adult ...
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Imperial College Healthcare Trust
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