Found 16 matching trials
A Study to Compare the Safety and Efficacy of an Aromatase Inhibitor in Combination With Lapatinib, Trastuzumab or Both for the Treatment of Hormone Receptor Positive, HER2+ Metastatic Breast Cancer PHASE3 A study to compare the safety and efficacy of an aromatase inhibitor in com...
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Novartis Investigative Site
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Fulvestrant With or Without Lapatinib and/or Aromatase Inhibitor Therapy in Treating Postmenopausal Women With Metastatic Breast Cancer That Progressed After Previous Aromatase Inhibitor Therapy PHASE3 RATIONALE: Estrogen can cause the growth of breast cancer cells. Hormone th...
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Federico II University Medical School
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Study Comparing Lapatinib (GW572016) And Letrozole Versus Letrozole In Subjects With Advanced Or Metastatic Breast Cancer PHASE3 This study evaluated and compared the efficacy and tolerability of lapatini...
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Novartis Investigative Site
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AUY922 With Lapatinib and Letrozole for ER+ HER2+ Advanced Breast Cancer PHASE1 The purpose of this study is to find out what effects, administering infusi...
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Multiple Locations
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Neoadjuvant Combined Endocrine and HER2 Target Therapy in Postmenopausal Women With ER and Her2 Positive Breast Cancer PHASE2 Cross-talk between epidermal growth factors and the ER occurs at multiple l...
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Asan Nedical Center
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PAM50 HER2-enriched Phenotype as a Predictor of Response to Dual HER2 Blockade in HER2-positive Early Breast Cancer PHASE2 Non-randomized, open label, multicentric translational research study in wo...
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Hospital de Torrevieja
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Extension Study of Lapatinib Plus Herceptin With or Without Endocrine Therapy PHASE2 Breast cancer is the most common malignancy in the U.S. Targeted therapies ...
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Active Not Recruiting
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University of Alabama - Birmingham
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A Randomized Phase II Trial Comparing Therapy Based on Tumor Molecular Profiling Versus Conventional Therapy in Patients With Refractory Cancer PHASE2 SHIVA is a proof of concept randomized phase II trial which compares two tr...
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Centre régional de lutte contre le cancer de Bourgogne Georges François Leclerc
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Efficacy and Safety of BMS-690514 in Combination With Letrozole to Treat Metastatic Breast Cancer PHASE2 The purpose of this study is to determine if BMS-690514 + letrozole will be...
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Texas Oncology-Abilene
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DETECT III - A Multicenter, Phase III Study to Compare Standard Therapy +/- Lapatinib in HER2-ve MBC-Patients With HER2+ve CTCs PHASE3 The HER2 status in breast cancer patients may change during the course of t...
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University Hospital Ulm
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